Related Experiment Video
Updated: Dec 22, 2025
09:53
Herbal Munziq Ameliorates Myocardial Ischemia-Reperfusion Injury by Inhibiting Inflammation
Published on: January 10, 2025
743
Muriolide, a novel antioxidant lactone from Ranunculus muricatus
Naila Raziq1, Muhammad Saeed2, Muhammad Shaiq Ali3
1Department of Pharmacy, Sarhad University of Science and Information Technology, Peshawar, Pakistan.
Natural Product Research
|May 1, 2020
Abstract:
Muriolide (1), a new aromatic lactone, has been isolated from the ethyl acetate fraction of Ranunculus muricatus. The compound was structurally characterized with the help of UV, IR, mass, 1D- and 2D-NMR data. It was tested in vitro for antioxidant and lipoxygenase inhibitory potential. Compound 1 showed good DPPH radical scavenging activity (IC50=56.9 μM), however it was moderately active against lipoxygenase enzyme (IC50=68.3 μM).