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Craniofacial resection for anterior skull base tumors
1St. Lukes/Roosevelt Hospital Center, New York, New York.
Head & Neck Surgery
|March 1, 1988
Summary
Craniofacial resection effectively treats anterior skull base tumors, including those with limited intracranial invasion. Survival varies by tumor type and grade, but the approach offers successful outcomes with minimal mortality.
Area of Science:
- Neurosurgery
- Oncology
- Otorhinolaryngology
Background:
- Anterior skull base tumors present complex surgical challenges.
- Craniofacial resection is a key surgical approach for these tumors.
- Understanding outcomes based on histology and invasion is crucial.
Purpose of the Study:
- To evaluate the outcomes of anterior skull base tumor resection using a craniofacial approach.
- To analyze survival rates based on tumor histology and intracranial invasion.
- To assess the safety and efficacy of the craniofacial approach.
Main Methods:
- Retrospective review of 30 patients with anterior skull base tumors.
- Surgical treatment via craniofacial resection over an 11-year period.
- Analysis of patient data including histology, intracranial invasion, and survival.
Main Results:
- The study included 30 patients with diverse tumor types (epithelial, sarcoma, esthesioneuroblastoma).
- 10 patients had intracranial invasion at the time of surgery.
- The overall median survival was 5 years, influenced by histology and tumor grade.
- The craniofacial approach demonstrated minimum operative mortality.
Conclusions:
- Craniofacial resection is a viable and successful treatment for anterior skull base malignancies.
- Limited intracranial invasion does not preclude successful resection if morbidity is minimized.
- Tumor histology and grade are significant prognostic factors for survival.
