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A possible connection between circulating 25-hydroxy-vitamin D and molecular response in chronic myeloid leukemia
Objective:
In this study we aimed to evaluate whether there is a link between circulating 25-OH-D levels and molecular response in chronic myeloid leukemia (CML).
Material And Method:
A total of 61 patients with CML (31 women, 30 men) were recruited in this cross-sectional study.
Results:
Binary logistic regression analysis demonstrated that increased vitamin D levels were independently associated with molecular response in subjects with CML.
Conclusion:
Our results indicated for the first time in the literature that severe deficiency of vitamin D was independently associated with molecular unresponsiveness in subjects with CML. 25-OH-D may be contributing to molecular response in the patients (Tab. 3, Ref. 24).
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