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Updated: Dec 22, 2025

Design of Cecal Ligation and Puncture and Intranasal Infection Dual Model of Sepsis-Induced Immunosuppression
Published on: June 15, 2019
[IgA vasculitis secondary to Klebsiella pneumoniae infection]
P Castan1, G Maigne1, J Boutemy1
1Service de médecine interne et immunologie clinique, CHU de Caen Côte de Nacre, 14000 Caen, France.
Introduction:
IgA vasculitis is a leucocytoclastic vasculitis of small vessels with immune deposits of IgA. It tends to occur in a post-infectious context, though the pathogenic agent is rarely found.
Observation:
We report, for the first time, the case of an 81-year old patient who presented with an acute IgA vasculitis with cutaneous and joint involvement during a Klebsiella pneumoniae respiratory infection. Remission of vasculitis was observed after antibiotic therapy alone.
Conclusion:
This observation reminds us of the need to search carefully for any pathogenic agent that may be driving IgA vasculitis as this may be important both for understanding aetiology and for treatment.
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