Sexual dysfunction in Neuro-Behcet's disease

The aim of the study was evaluation of sexual dysfunction in neuro-Behcet's disease (NBD). A total of 25 patients with NBD, 22 patients with Behçet's disease (BD) without neurologic involvement (BDWONI) and 19 persons in control group were prospectively included in the study. We collected all demographic data. A semi-structured interview guided by a Arizona sexual experience scale (ASEX) questionnaire, Beck Depression Inventory and Beck Anxiety Inventory was applied to all of the patients. The sexual dysfunction was significantly higher in patients with NBD (47.9%) compared to patients with BDWONI (35.4%) and control group (16.7%) (p = 0.001). The score of total ASEX, drive, aurosal, vaginal lubrication/penil erection and satisfaction from orgasm were significantly higher in patients with NBD than healthy control group, statistically. Just arousal and lubrication/penile erection scores were significantly higher in NBD group than BDWONI group. Female/Male ratio regarding sexual dysfunction was 43.5/56.5, 29.4/70.6, 62.5/37.5 in NBD, BDWONI and healthy control group, respectively (0 = 0.027). NBD had a negative effect on sexuality in all but especially on arousal and vaginal lubrication/penil erection function based on ASEX questionnaire. Moreover, male sexuality was more affected by BD than female sexuality. Further researches using larger sample sizes are needed to clarify the issues.