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Updated: Dec 22, 2025

Drug-Induced Sleep Endoscopy DISE with Target Controlled Infusion TCI and Bispectral Analysis in Obstructive Sleep Apnea
Published on: December 6, 2016
Sleep endoscopy findings in children in supine versus left lateral position
1Jacobs School of Medicine and Biomedical Sciences at the University at Buffalo, Department of Otolaryngology-Head and Neck Surgery, USA.
Insights
Lateral positioning during drug-induced sleep endoscopy (DISE) significantly improves airway patency in children with obstructive sleep apnea (OSA), especially at the base of the tongue and larynx. This positional change offers a valuable diagnostic insight for pediatric OSA management.
Area of Science:
- Pediatric Otolaryngology
- Sleep Medicine
- Diagnostic Imaging
Background:
- Obstructive sleep apnea (OSA) is a common condition in children.
- Drug-induced sleep endoscopy (DISE) is a key diagnostic tool for OSA.
- Standard DISE positioning is typically supine, which may not reflect all airway dynamics.
Purpose of the Study:
- To evaluate the impact of lateral positioning on drug-induced sleep endoscopy (DISE) findings in pediatric obstructive sleep apnea (OSA).
- To compare upper airway obstruction patterns in supine versus left lateral positions during DISE.
Main Methods:
- A cohort of 63 children with OSA undergoing DISE was studied.
- Patients were assessed in both supine and left lateral (LL) positions.
- Obstruction sites (palate, tonsils, base of tongue, larynx) were compared between positions.
Main Results:
- Lateral positioning led to improved airway patency in 60.3% of patients, particularly at the base of the tongue and larynx.
- Obstruction at the base of the tongue and larynx improved in 54% of patients when moving from supine to LL position.
- While some sites improved, others could worsen, highlighting complex positional effects on airway collapse.
Conclusions:
- Left lateral positioning during DISE can significantly enhance airway patency in children with OSA.
- This positional maneuver provides critical information for surgical planning and understanding pediatric OSA.
- DISE in lateral decubitus may reveal alternative airway routes not evident in supine positioning.
Objective:
To describe how drug-induced sleep endoscopy (DISE) findings in children with obstructive sleep apnea (OSA) change with lateral positioning.
Methods:
Children undergoing DISE for OSA in 2018-19 at a tertiary care children's hospital were positioned first supine and then in left lateral (LL) and findings were compared.
Results:
63 children were included, 30 (47.6%) female and 33 (52.4%) male, mean age 4.64 years, and a mean Z-score 0.70. Mean pre-op Apnea Hypopnea Index (AHI) was 6.41 and REM AHI was 15.04. In supine position, 20 had obstruction at the palate (31.7%), 39 (61.9%) had obstruction at each of the base of tongue and the larynx, 17 (27.0%) had obstruction at the tonsils. In LL position, 11 (17.5%) were obstructed at the palate, 21 (33.3%) at the tonsils, 8 (12.7%) at the base of tongue and 7 (11.1%) at the larynx. Larynx and base of tongue were most likely to improve in LL position, as 54% of patients obstructed in supine position were open in LL position. Overall 38 (60.3%) patients improved on LL, 18 (28.6%) had no change, and 7 (11.1%) worsened. 30 (47.6%) patients improved in 1 site while 12 (19.0%) improved in more than 1 site. 16 (25.4%) patients worsened in 1 site and 9 (56.3%) of these had improvement in another site.
Conclusion:
A significant number of patients improved airway patency, particularly at the base of tongue/larynx, during DISE when placed in LL position as compared to standard supine positioning.
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