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Updated: Dec 22, 2025

Expedited Radiation Biodosimetry by Automated Dicentric Chromosome Identification ADCI and Dose Estimation
Published on: September 4, 2017
A multicentric IT platform for storage and sharing of imaging-based radiation dosimetric data
Joël Spaltenstein1, Nicolas van Dooren2, Gérôme Pasquier3
1Swiss Institute of Bioinformatics, Geneva, Switzerland. spalte@naturalimage.ch.
The MEDIRAD project developed a platform for sharing medical images and radiation dose data from procedures. This system integrates imaging and dosimetric information, aiding low-dose radiation research.
Area of Science:
- Medical Imaging
- Radiation Dosimetry
- Health Informatics
Background:
- Researching the effects of low radiation doses from medical procedures is crucial.
- Existing data management systems often lack integration between imaging and dosimetric data.
Purpose of the Study:
- To develop an informatics service for the MEDIRAD project.
- To create a platform for sharing medical images and associated dosimetric data.
Main Methods:
- Designed an integrated system architecture for managing image and dosimetric data.
- Utilized separate repositories for DICOM and non-DICOM data.
- Implemented a semantic database linked via an ontology to connect data.
Main Results:
- The system supports CT, PET, SPECT, and NM images, along with dose reports.
- Integrated workflows for Monte Carlo-based organ dose calculations (Chest CT) and radionuclide therapy dose estimations (thyroid).
Conclusions:
- The informatics service is deployed, providing MEDIRAD users access to integrated image and dosimetric data.
- The system's design allows for reuse in similar research projects.
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