[Features of chronic kidney disease in elderly patients.]

The purpose of the work is to study the characteristics of the course of chronic kidney disease in elderly patients based on the analysis of the register of chronic kidney disease (CKD) for 2015-2018. in the Department of Nephrology, the Komi Republican Clinical Hospital. There are 484 patients in the register, of whom 231 are men (47,7%), 253 women (52,3%). The average age is 58,8±15,8 years old. The patients were divided into 3 groups: persons under the age of 59 years old - 218 people (group 1); from 60 to 74 years old - 207 people (group 2); and over 75 years old - 59 people (group 3). Most patients are between the ages of 60 and 69 years old. In the 1st group, the chronic glomerulonephritis is the leading cause of CKD - 27,1%; in the 2nd group - the chronic tubulo-interstitial nephritis (TIN) - 21,7%, the diabetic nephropathy (DN) - 20,8% and the hypertensive nephropathy - 15,9%; in the 3d group - TIN (27,1%), the chronic pyelonephritis (PN) (15,9%) and DN (13,6%). With increasing age, the incidence of TIN (p<0,1), MO (p<0,05), coronary kidney disease (IBP) (p<0,05), gouty nephropathy (p<0,1) were raised. The average reduction in GFR is 3,99 ml/min/1,73 m2 per year of observation. The rate of decline in GFR in the 1st group is 3,36±1,8 ml/min/1,73 m2 per year, in the 2nd - 2,43±1,2 (p<0,001 between group 1 and 2), in the 3rd group - 1,82±1,1; with aging the negative correlation was observed (p<0,05). 39 patients received hemodialysis, including: in the 1st group - 20 people (9%), in the 2nd group - 18 (8,7%), in the 3rd group - 1 patient (1,7%). Making the register of the patients with CKD allows us to know the number of patients and the causes of CKD among the patients of elderly and senile ages, to assess the clinical situation, the rate of decline in GFR and treatment tactics in these patients.