Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Multimodal neuromonitoring in neonatal hypoxic-ischemic encephalopathy and the association with neurodevelopmental outcomes: A Multicenter Study.

The Journal of pediatrics·2026
Same author

Objective quality assessment for precision functional MRI data.

Neuron·2026
Same author

Unraveling the Complexity of Multilingual Comprehension: Neuroimaging and Linguistic Profiling in 700+ Adults.

Scientific data·2026
Same author

Effect of sleep stage on patterns of fNIRS hemodynamic response to auditory paradigms in 1-month-old Gambian and UK infants.

Neurophotonics·2026
Same author

Double-Blind Placebo-Controlled Randomized Study of Sporopollenin Exine (SpEC) Fragrance Encapsulation.

Pharmaceutics·2026
Same author

Prenatal Volume in the Bilateral Superior Temporal Gyrus Associates With Children's Expressive Vocabulary at 24-36 Months.

Developmental science·2026

Related Experiment Video

Updated: Dec 22, 2025

Cerebral Blood Flow-Based Resting State Functional Connectivity of the Human Brain using Optical Diffuse Correlation Spectroscopy
07:13

Cerebral Blood Flow-Based Resting State Functional Connectivity of the Human Brain using Optical Diffuse Correlation Spectroscopy

Published on: May 27, 2020

7.0K

Sleep State Modulates Resting-State Functional Connectivity in Neonates.

Chuen Wai Lee1,2, Borja Blanco3,4, Laura Dempsey1,3

  • 1neoLAB, The Evelyn Perinatal Imaging Centre, The Rosie Hospital, Cambridge University Hospitals NHS Foundation Trust, Cambridge, United Kingdom.

Frontiers in Neuroscience
|May 5, 2020
PubMed
Summary
This summary is machine-generated.

Infant brain activity shows distinct resting-state networks (RSNs) during active sleep (AS) and quiet sleep (QS). Researchers found differences in connectivity patterns between these sleep states, highlighting the importance of monitoring sleep in infant neuroimaging studies.

Keywords:
connectomefunctional imagingfunctional near-infrared spectroscopyneonatesresting-state functional connectivitysleep state

More Related Videos

Resting-State Connectivity and Neuroimaging of Prefrontal Cortex Activity During a Block-Design Yoga Asana Practice Using fNIRS
07:56

Resting-State Connectivity and Neuroimaging of Prefrontal Cortex Activity During a Block-Design Yoga Asana Practice Using fNIRS

Published on: June 24, 2025

718
Application of an Amplitude-integrated EEG Monitor Cerebral Function Monitor to Neonates
05:58

Application of an Amplitude-integrated EEG Monitor Cerebral Function Monitor to Neonates

Published on: September 6, 2017

40.3K

Related Experiment Videos

Last Updated: Dec 22, 2025

Cerebral Blood Flow-Based Resting State Functional Connectivity of the Human Brain using Optical Diffuse Correlation Spectroscopy
07:13

Cerebral Blood Flow-Based Resting State Functional Connectivity of the Human Brain using Optical Diffuse Correlation Spectroscopy

Published on: May 27, 2020

7.0K
Resting-State Connectivity and Neuroimaging of Prefrontal Cortex Activity During a Block-Design Yoga Asana Practice Using fNIRS
07:56

Resting-State Connectivity and Neuroimaging of Prefrontal Cortex Activity During a Block-Design Yoga Asana Practice Using fNIRS

Published on: June 24, 2025

718
Application of an Amplitude-integrated EEG Monitor Cerebral Function Monitor to Neonates
05:58

Application of an Amplitude-integrated EEG Monitor Cerebral Function Monitor to Neonates

Published on: September 6, 2017

40.3K

Area of Science:

  • Neuroscience
  • Developmental Neuroscience
  • Infant Brain Development

Background:

  • Resting-state networks (RSNs) reflect spontaneous cerebral activity and are well-studied in infants.
  • The impact of sleep state on infant RSNs remains under-investigated, despite sleep's known effects on connectivity in adults.
  • Most infant neuroimaging relies on sustained sleep, making sleep state a critical factor.

Purpose of the Study:

  • To investigate the influence of sleep state (active sleep vs. quiet sleep) on resting-state networks (RSNs) in neonates.
  • To determine if sleep state affects functional connectivity patterns in the infant brain.
  • To assess the importance of sleep state monitoring in infant neuroimaging studies.

Main Methods:

  • Simultaneous monitoring of sleep state using electroencephalography (EEG) and functional near-infrared spectroscopy (fNIRS).
  • Analysis of resting-state functional connectivity in healthy, term-born neonates during active sleep (AS) and quiet sleep (QS).
  • Utilized three independent functional connectivity analyses to ensure robust findings.

Main Results:

  • Infant neonates exhibited functional connectivity patterns consistent with known RSN structures during both AS and QS.
  • Interhemispheric connectivity was significantly stronger during AS compared to QS.
  • Short-range, within-hemisphere functional connectivity appeared enhanced during QS.

Conclusions:

  • Sleep state significantly influences resting-state network organization in neonates.
  • Active sleep is associated with increased interhemispheric connectivity, while quiet sleep shows enhanced within-hemisphere connectivity.
  • Monitoring sleep state is crucial for accurate interpretation of RSNs in infant neuroimaging research.