Diazepam Premedication in Primary Augmentation Mammoplasty
Elizabeth A Lucich1, Nicholas S Adams1, Renee L Barry2
1Spectrum Health/Michigan State University Plastic Surgery Residency, Grand Rapids.
Eplasty
|May 5, 2020
Summary
Preoperative oral diazepam did not significantly improve recovery times for breast augmentation patients. This study found that diazepam may increase postoperative narcotic use and pain scores, suggesting it is not beneficial for this procedure.
Area of Science:
- Plastic Surgery
- Anesthesiology
- Pharmacology
Background:
- Outpatient surgical centers are increasingly utilized for elective procedures like breast augmentation.
- Preoperative anxiolytics, such as diazepam, are sometimes administered to manage patient anxiety.
- The impact of preoperative diazepam on the postoperative recovery course in augmentation mammoplasty requires further evaluation.
Purpose of the Study:
- To assess the effect of preoperative oral diazepam on the postoperative recovery of patients undergoing primary augmentation mammoplasty.
- To compare pain scores, medication requirements, and discharge times between patients receiving diazepam and a control group.
Main Methods:
- Retrospective review of 189 patients undergoing primary breast augmentation between 2012 and 2015.
- Comparison of a group receiving oral diazepam premedication with a control group.
- Collection of data on demographics, perioperative medications, operative details, and postoperative pain scores.
Main Results:
- No significant differences in age, BMI, implant size, or intraoperative opioid use between groups.
- Operative time was slightly longer in the control group (P = .006).
- Postoperative narcotic use (P = .036) and predischarge pain scores (P = .006) were higher in the diazepam group, with no significant reduction in discharge time.
Conclusions:
- Preoperative oral diazepam does not significantly reduce discharge time in primary augmentation mammoplasty.
- The use of diazepam in this context may lead to increased postoperative narcotic consumption and elevated pain levels at discharge.
- Current evidence does not support the routine use of preoperative diazepam for primary breast augmentation in outpatient settings.
Related Concept Videos
Cardiomyopathy VII: Pre and Post Operative Nursing Management
199
Patients with hypertrophic cardiomyopathy (HCM) and left ventricular outflow tract (LVOT) obstruction who remain symptomatic despite optimal medical therapy may undergo a septal myectomy (Morrow procedure). This procedure involves excising a portion of the hypertrophied septum below the aortic valve using a heart-lung machine to improve blood flow through the LVOT. Effective preoperative and postoperative nursing management ensures successful patient outcomes, minimizes complications, and...
199
Parenteral Anesthetics: Overview
505
Intravenous anesthetics are drugs administered parenterally to induce anesthesia or sedation. Propofol is a widely used agent formulated as a 1% emulsion in soybean oil, glycerol, and egg phosphatide. It induces rapid anesthesia primarily due to its rapid distribution from the bloodstream to target tissues and is metabolized in the liver. However, it can cause significant pain on injection and hypertriglyceridemia. Fospropofol, a water-based prodrug of propofol, lacks these adverse effects.
505
Radiological Investigation III: Pulmonary Angiogram and PET Scan
330
Radiological investigations are paramount in the diagnosis and management of various pulmonary diseases. Two essential investigations are the Pulmonary Angiogram and the Positron Emission Tomography (PET) Scan.
Pulmonary Angiogram
A Pulmonary Angiogram is an invasive procedure involving injecting a contrast medium through a catheter threaded into the pulmonary artery or the right side of the heart to visualize the pulmonary vasculature. Computed Tomography (CT) scans have mainly replaced this...
Pulmonary Angiogram
A Pulmonary Angiogram is an invasive procedure involving injecting a contrast medium through a catheter threaded into the pulmonary artery or the right side of the heart to visualize the pulmonary vasculature. Computed Tomography (CT) scans have mainly replaced this...
330
Aneurysm IV: Nursing Management
300
Vigilant monitoring for aneurysm rupture is essential for patients undergoing aortic surgery.Preoperative Nursing ManagementContinuously monitor the patient for manifestations of aneurysm rupture, such as pallor, weakness, tachycardia, hypotension, abdominal, back, groin, or periumbilical pain, changes in consciousness, and a pulsating abdominal mass. Regularly assess the patient's peripheral pulses.Instruct the patient to consume a clear liquid diet the day before surgery and administer...
300
Skeletal Muscle Relaxants: Therapeutic Uses
804
Skeletal muscle relaxants are used to relax muscle tone and alleviate painful muscle contractions. However, the choice of skeletal muscle relaxants depends on the duration of the surgical procedure in order to minimize potential side effects. Skeletal muscle relaxants like neuromuscular blocking agents [NMBAs] are commonly employed as adjuvants alongside general anesthetics in clinical settings. NMBAs are also used to maintain controlled ventilation during surgery of the larynx or pharynx...
804
Depolarizing Blockers: Pharmocokinetics
522
Depolarizing blockers are administered through intravenous injection. Succinylcholine is the most common choice of depolarizing blockers in emergency clinical practices. Although they have a rapid onset, they readily diffuse away from the motor end plate into the extracellular fluid. They are metabolized by enzymes such as liver butyrylcholinesterase and plasma pseudocholinesterases. This produces a short duration of action, typically 5-10 minutes long, unlike nondepolarizing blockers, which...
522


