Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Biological Methods for Microbial Control01:28

Biological Methods for Microbial Control

706
Biological agents offer an effective means of controlling microbial growth by leveraging natural processes like predation, competition, and the secretion of antimicrobial substances.Predatory bacteria such as Bdellovibrio species target and kill pathogens like Salmonella and E. coli. They are widely used in poultry farms to control infections. Myxococcus species help combat plant-pathogenic fungi. These naturally occurring predators serve as eco-friendly alternatives to chemical pesticides and...
706
Antimicrobial Proteins01:23

Antimicrobial Proteins

12.8K
Antimicrobial proteins are important components of the immune system. They aid the body in combating pathogens by either killing them directly or hindering their replication processes. Four main types of antimicrobial substances are interferons, the complement system, iron-binding proteins, and antimicrobial proteins.
Interferons
Interferons (IFNs) are proteins produced by lymphocytes, macrophages, and fibroblasts infected with viruses. While IFNs cannot prevent viruses from entering and...
12.8K
Chemical Agents for Microbial Control01:27

Chemical Agents for Microbial Control

656
Chemicals play important roles in controlling microbial growth by targeting microbial structures and functions as sanitizers, antiseptics, disinfectants, and sterilants.Alcohols are commonly used sanitizers, effectively disrupting lipid membranes, which compromises cell integrity. They are also used as antiseptics and disinfectants due to their rapid action and versatility.Phenols and their derivatives phenolics , known for denaturing proteins and disrupting cell membranes, are particularly...
656
Antimicrobial Effectiveness01:28

Antimicrobial Effectiveness

843
The effectiveness of antimicrobial agents depends on various factors influencing their ability to eliminate microbial populations. Larger microbial populations require more time for complete eradication, emphasizing the importance of population size analysis when evaluating antimicrobial efficacy.Microbial resistance to antimicrobial agents varies significantly. Highly resilient microorganisms include endospores, gram-negative bacteria, and non-enveloped viruses, while prions are exceptionally...
843
Gene Regulation in Microbial Communities: Quorum Sensing01:28

Gene Regulation in Microbial Communities: Quorum Sensing

399
Quorum sensing is a mechanism of bacterial communication that enables coordinated gene expression in response to changes in population density. This facilitates collective behaviors that enhance survival, resource acquisition, and ecological adaptation. This process relies on small signaling molecules called autoinducers that accumulate as bacterial populations grow. When a critical threshold concentration of autoinducers is reached, bacterial cells collectively modify gene expression,...
399

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Critical re-evaluation of experimental settings with fluorescent probes for bioorthogonal chemistry with palladium antimony inactivation-resistant catalyst.

Scientific reports·2026
Same author

Prolonged zinc exposure modulates biofilm metabolic activity and conjugation in Enterococcus faecalis.

BMC microbiology·2026
Same author

Equine sentinels and one health: a comprehensive serological survey of Crimean-Congo hemorrhagic fever virus in southeastern and Central Europe.

Frontiers in veterinary science·2026
Same author

Tick-borne pathogens in Ixodes ricinus (Acari: Ixodidae) and Ixodes inopinatus × I. ricinus hybrids in Central Europe: no link to bird diversity or abundance.

Journal of medical entomology·2026
Same author

Cellulose Acetate Fibers With Infiltrated ZnO Nanocrystals: Activation of Antibacterial Properties Against Acne vulgaris by Oxygen Plasma Treatment.

Small (Weinheim an der Bergstrasse, Germany)·2026
Same author

Ultrasound-Responsive Dual-Prodrug Nanoassembly for "Fenestrae-Restoration Strategy" in Liver Fibrosis Therapy.

Advanced materials (Deerfield Beach, Fla.)·2026

Related Experiment Video

Updated: Dec 22, 2025

Antimicrobial Characterization of Advanced Materials for Bioengineering Applications
08:08

Antimicrobial Characterization of Advanced Materials for Bioengineering Applications

Published on: August 4, 2018

22.7K

Nanomaterials with active targeting as advanced antimicrobials.

Kristyna Smerkova1,2, Kristyna Dolezelikova1,2, Lucie Bozdechova1,2

  • 1Department of Chemistry and Biochemistry, Mendel University in Brno, Brno, Czech Republic.

Wiley Interdisciplinary Reviews. Nanomedicine and Nanobiotechnology
|May 5, 2020
PubMed
Summary

Antimicrobial nanomaterials offer a promising alternative to antibiotics, overcoming resistance through multiple mechanisms or acting as nanocarriers. Targeting strategies enhance their efficacy and reduce side effects in treating bacterial infections.

Keywords:
biomimeticdeliverynanomedicinepeptideresistance

More Related Videos

Synthesis of Multi-walled Carbon Nanotubes Modified with Silver Nanoparticles and Evaluation of Their Antibacterial Activities and Cytotoxic Properties
11:19

Synthesis of Multi-walled Carbon Nanotubes Modified with Silver Nanoparticles and Evaluation of Their Antibacterial Activities and Cytotoxic Properties

Published on: May 10, 2018

10.6K
Evaluation of Antimicrobial Activities of Nanoparticles and Nanostructured Surfaces In Vitro
11:52

Evaluation of Antimicrobial Activities of Nanoparticles and Nanostructured Surfaces In Vitro

Published on: April 21, 2023

3.8K

Related Experiment Videos

Last Updated: Dec 22, 2025

Antimicrobial Characterization of Advanced Materials for Bioengineering Applications
08:08

Antimicrobial Characterization of Advanced Materials for Bioengineering Applications

Published on: August 4, 2018

22.7K
Synthesis of Multi-walled Carbon Nanotubes Modified with Silver Nanoparticles and Evaluation of Their Antibacterial Activities and Cytotoxic Properties
11:19

Synthesis of Multi-walled Carbon Nanotubes Modified with Silver Nanoparticles and Evaluation of Their Antibacterial Activities and Cytotoxic Properties

Published on: May 10, 2018

10.6K
Evaluation of Antimicrobial Activities of Nanoparticles and Nanostructured Surfaces In Vitro
11:52

Evaluation of Antimicrobial Activities of Nanoparticles and Nanostructured Surfaces In Vitro

Published on: April 21, 2023

3.8K

Area of Science:

  • Nanomedicine
  • Infectious Disease Therapeutics
  • Drug Discovery

Background:

  • Antibiotic resistance poses a significant global health threat.
  • Nanomaterials are being explored as alternatives to conventional antibiotics.
  • Current strategies include direct antimicrobial action and nanocarrier systems for antibiotics.

Purpose of the Study:

  • To review the advantages, disadvantages, and challenges of using nanomaterials for antimicrobial applications.
  • To discuss various targeting strategies for nanomaterials in treating bacterial infections.
  • To highlight the potential of nanomedicine in overcoming antibiotic resistance.

Main Methods:

  • Literature review focusing on nanomaterials in antimicrobial therapy.
  • Analysis of different targeting strategies (passive and specific) for nanomaterials.
  • Discussion of mechanisms of action and nanocarrier applications.

Main Results:

  • Nanomaterials can combat bacteria via multiple simultaneous mechanisms, potentially overcoming resistance.
  • Nanomaterials can serve as effective nanocarriers for antibiotics, bypassing bacterial defense mechanisms.
  • Targeting strategies, particularly specific targeting, improve antimicrobial efficacy and minimize side effects.

Conclusions:

  • Nanomaterials represent a versatile platform for developing novel antimicrobial agents and drug delivery systems.
  • Effective targeting strategies are crucial for maximizing the therapeutic potential of nanomaterials in infectious disease treatment.
  • Further research is needed to address the challenges and fully realize the benefits of nanomedicine for combating bacterial infections.