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Updated: Dec 22, 2025

Visualization of IL-22-expressing Lymphocytes Using Reporter Mice
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Interleukin-22 and intestinal homeostasis: Protective or destructive?

Mojtaba Shohan1,2, Razieh Dehghani3, Ali Khodadadi1

  • 1Department of Immunology, Faculty of Medicine, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.

IUBMB Life
|May 5, 2020
PubMed
Summary

Interleukin (IL)-22, a cytokine mainly secreted by Th22 cells, plays a dual role in gut homeostasis and inflammation. Emerging research highlights its involvement in various diseases and potential for treating intestinal disorders.

Keywords:
IL-22colon cancerinflammatory bowel diseasesintestinal homeostasis

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