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Related Concept Videos

Myocarditis II: Clinical Features and Diagnostic Tests01:27

Myocarditis II: Clinical Features and Diagnostic Tests

181
Myocarditis is an inflammation of the heart muscle. The symptoms vary widely, encompassing asymptomatic presentations to severe, acute manifestations.Clinical PresentationAsymptomatic cases: In some instances, myocarditis may be asymptomatic, with the infection resolving without intervention. These cases often go undetected unless discovered incidentally through diagnostic imaging or tests conducted for other reasons.General Early Symptoms: Early symptoms of myocarditis are non-specific and can...
181
ECG Interpretation of Arrhythmias I: Sinus Arrhythmias01:16

ECG Interpretation of Arrhythmias I: Sinus Arrhythmias

641
Arrhythmias are disturbances in the heart's rhythm that lead to abnormal heartbeats. These irregularities can originate from different parts of the heart and are classified based on their origin and nature.
Types of Arrhythmias
Sinus Node Arrhythmias
Sinus Bradycardia: Originating from the sinoatrial (SA) node, sinus bradycardia involves slower impulses, resulting in a heart rate of less than 60 beats per minute (bpm). Causes include sleep, vagal stimulation, beta-blockers, hypothyroidism,...
641
Myocarditis III: Medical Management01:14

Myocarditis III: Medical Management

117
Myocarditis: Comprehensive Medical ManagementMyocarditis, the heart muscle inflammation, requires a comprehensive medical management strategy that addresses the underlying cause, provides supportive care, manages symptoms, and reduces cardiac workload.Infections and Autoimmune CausesAdminister appropriate antimicrobial therapy when an infectious agent causes myocarditis. For instance, penicillin treats infections caused by Group A Streptococcus. In cases where autoimmune processes are...
117
Endocarditis II: Clinical Features of Infective Endocarditis01:25

Endocarditis II: Clinical Features of Infective Endocarditis

281
Endocarditis can present various clinical features depending on the causative organism and the patient's underlying health conditions. Initially, the clinical features of infective endocarditis develop gradually, presenting with nonspecific symptoms that can be easily mistaken for other illnesses.General SymptomsEarly symptoms of infective endocarditis are fever, chills, weakness, malaise, fatigue, and weight loss. These symptoms reflect the systemic nature of the infection and the body's...
281
Rheumatic Heart Disease II: Clinical Manifestations and Diagnostic Studies01:22

Rheumatic Heart Disease II: Clinical Manifestations and Diagnostic Studies

342
The key clinical manifestations of Rheumatic heart disease (RHD) include several distinct cardiac symptoms.Carditis, a hallmark of acute rheumatic fever, involves inflammation of the heart's endocardium, myocardium, and pericardium. Chronic RHD often results from recurrent episodes of carditis. Its symptoms include the following:Murmurs are caused by valvular damage, especially to the mitral and aortic valves. Mitral stenosis or regurgitation is common, with characteristic heart murmurs...
342
Pericarditis II: Clinical Features and Diagnostic Tests01:19

Pericarditis II: Clinical Features and Diagnostic Tests

215
Pericarditis is distinguished by inflammation of the pericardium, the fibrous sac that encases the heart. It can be acute, lasting less than six weeks, or chronic, persisting for over three months. Understanding its clinical manifestations and diagnostic findings is crucial for timely and effective management.Clinical ManifestationsWhile pericarditis can be asymptomatic, it usually presents with characteristic symptoms such as:Chest Pain: The most characteristic symptom of pericarditis is chest...
215

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Updated: Dec 22, 2025

Microelectrode Array Recording of Sinoatrial Node Firing Rate to Identify Intrinsic Cardiac Pacemaking Defects in Mice
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Possible Lyme Carditis with Sick Sinus Syndrome.

Brian Cheung1, Larry Lutwick2, Michelle Cheung3

  • 1Saint Bernards Healthcare, 300 Carson St., Jonesboro, AR, 72401, United States.

Idcases
|May 6, 2020
PubMed
Summary
This summary is machine-generated.

This case study highlights a rare presentation of Lyme carditis, focusing on sick sinus syndrome (SSS) without atrioventricular block (AVB) in a Lyme disease patient. It emphasizes considering Lyme carditis in endemic areas with new-onset bradycardia.

Keywords:
BradycardiaLyme CarditisLyme DiseaseSick Sinus Syndrome

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Area of Science:

  • Infectious Diseases
  • Cardiology
  • Neurology

Background:

  • Lyme disease, caused by *Borrelia burgdorferi*, is transmitted by *Ixodes* ticks and can lead to Lyme carditis.
  • Lyme carditis commonly presents with bradycardia due to atrioventricular block (AVB).

Observation:

  • A 47-year-old man with Lyme disease presented with headache, new-onset bradycardia, and right cranial nerve VI palsy causing diplopia.
  • Diagnostic tests confirmed *Borrelia burgdorferi* infection.
  • Electrocardiography (EKG) revealed severe bradycardia (heart rate in the 30s BPM) with pauses but no AVB.

Findings:

  • The patient was diagnosed with sick sinus syndrome (SSS) without AVB, a rare cardiac manifestation of Lyme disease.
  • The patient responded well to antibiotic therapy with doxycycline.

Implications:

  • This case expands the spectrum of cardiac presentations of Lyme carditis beyond AVB.
  • Clinicians should consider Lyme carditis in patients from endemic areas presenting with new-onset bradycardia, even without typical AVB.
  • Early diagnosis and treatment are crucial for managing Lyme carditis and its neurological complications.