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Updated: Dec 22, 2025
The Multiple Sclerosis Performance Test MSPT: An iPad-Based Disability Assessment Tool
Published on: June 30, 2014
Development and validation of the self-reported disability status scale (SRDSS) to estimate EDSS-categories
Marco Kaufmann1, Anke Salmen2, Laura Barin3
1Epidemiology, Biostatistics and Prevention Institute, University of Zurich, Zurich, Switzerland.
Background:
Clinician-assessed Expanded Disease Status Scale (EDSS) is gold standard in clinical investigations but normally unavailable in population-based, patient-centred MS-studies. Our objective was to develop a self-reported gait measure reflecting EDSS-categories.
Methods:
We developed the self-reported disability status scale (SRDSS) with three categories (≤3.5, 4-6.5, ≥7) based on three mobility-related questions. The SRDSS was determined for 173 persons with MS and validated against clinical EDSS to calculate sensitivity and specificity.
Results:
Accuracy was 88.4% (153 correctly classified) and weighted kappa 0.73 (0.62-0.84). Sensitivity/specificity-pairs were 94.5%/77.8%, 69.0%/94.7% and 100%/98.2% for SRDSS ≤3.5, 4-6.5 and ≥7, respectively.
Conclusions:
Self-reported SRDSS approximates EDSS-categories well and fosters comparability between clinical and population-based studies.
