Related Experiment Video
Updated: Dec 22, 2025
12:11
Capture Compound Mass Spectrometry - A Powerful Tool to Identify Novel c-di-GMP Effector Proteins
Published on: March 29, 2015
12.0K
Generic high-capacity protein capture and release by pH control
G Ferrand-Drake Del Castillo1, R L N Hailes, Z Adali-Kaya
1Department of Chemistry and Chemical Engineering, Chalmers University of Technology, Gothenburg, Sweden. adahlin@chalmers.se.
Chemical Communications (Cambridge, England)
|May 7, 2020
Abstract:
Techniques for immobilization and release of proteins are of general interest but challenging to develop. Here we show a new method for high-capacity (several μg cm-2) immobilization of proteins in polyelectrolyte brushes by multivalent hydrogen bonds. Upon increasing pH, the proteins are fully released with preserved structure and activity.
