Chilblain-like lesions in children following suspected COVID-19 infection

Cristiana Colonna1, Nicola Adriano Monzani2, Alessia Rocchi3

  • 1Pediatric Dermatology Department, IRCCS Foundation Cà Granda, Ospedale Maggiore Policlinico, Milan, Italy.

Insights

Mildly symptomatic children can develop chilblain-like skin lesions during COVID-19. Histology revealed vasculitis with fibrin thrombi in affected pediatric patients.

Area of Science:

  • Dermatology
  • Pediatrics
  • Infectious Diseases

Background:

  • The COVID-19 pandemic has seen various mucocutaneous manifestations.
  • Chilblain-like lesions, also known as 'COVID toes', have been observed in pediatric cases.

Observation:

  • This study details four children with suspected COVID-19 infection.
  • These children presented with acral skin findings and mild systemic symptoms.

Findings:

  • Histopathological examination of one case demonstrated vasculitis.
  • Evidence of fibrin thrombus was noted in the affected blood vessels.

Implications:

  • These findings suggest a potential link between COVID-19 and vasculitic skin reactions in children.
  • Understanding these dermatological manifestations is crucial for pediatricians during the pandemic.

Related Concept Videos

Endocarditis II: Clinical Features of Infective Endocarditis01:25

Endocarditis II: Clinical Features of Infective Endocarditis

Endocarditis can present various clinical features depending on the causative organism and the patient's underlying health conditions. Initially, the clinical features of infective endocarditis develop gradually, presenting with nonspecific symptoms that can be easily mistaken for other illnesses.General SymptomsEarly symptoms of infective endocarditis are fever, chills, weakness, malaise, fatigue, and weight loss. These symptoms reflect the systemic nature of the infection and the body's...
281
Myocarditis II: Clinical Features and Diagnostic Tests01:27

Myocarditis II: Clinical Features and Diagnostic Tests

Myocarditis is an inflammation of the heart muscle. The symptoms vary widely, encompassing asymptomatic presentations to severe, acute manifestations.Clinical PresentationAsymptomatic cases: In some instances, myocarditis may be asymptomatic, with the infection resolving without intervention. These cases often go undetected unless discovered incidentally through diagnostic imaging or tests conducted for other reasons.General Early Symptoms: Early symptoms of myocarditis are non-specific and can...
181
Acute Pharyngitis01:30

Acute Pharyngitis

Introduction
Acute pharyngitis is the inflammation of the back of the throat (pharynx), commonly resulting in a sore throat. It is a frequently encountered condition that prompts individuals to seek medical advice.
Classification
Acute pharyngitis can be categorized based on its underlying cause:
3.3K
Stages of Infection01:26

Stages of Infection

Stages of infection describe what happens to a susceptible host once a pathogen invades the human body. The stages of infection are incubation, prodromal, illness, stage of decline, and convalescence. The incubation stage is the period from exposure to a pathogen until symptoms start. The infected person is unaware of impending illness as the pathogens grow and multiply within the body. The duration may vary depending on the type of infection. The incubation period of measles averages ten to...
64.5K