[Evolution of followed renal oncocytomas]

Area of Science:

• Nephrology
• Oncology
• Pathology

Background:

• Renal oncocytomas are benign kidney tumors with incompletely understood growth patterns.
• Factors influencing the growth rate of renal oncocytomas require further investigation.

Purpose of the Study:

• To analyze the evolution and growth of renal oncocytomas after histological confirmation.
• To identify factors associated with the growth rate of these kidney tumors.

Main Methods:

• Retrospective study involving patients diagnosed with renal oncocytoma via percutaneous biopsy.
• Data collected included epidemiological, histological, and morphological factors.
• Pearson correlation analysis was used to determine factors influencing tumor growth.

Main Results:

• Fifty-three patients were included with a median follow-up of 34 months.
• Tumor growth averaged 0.25 cm/yr, with faster growth observed in younger patients and larger initial tumor sizes.
• A positive linear relationship existed between growth velocity and initial size (R=0.27, P=0.047).
• A negative linear relationship was found between growth velocity and age at diagnosis (ρ=-0.44, P<0.001).

Conclusions:

• Tumor growth rate is influenced by patient age and initial tumor size.
• Rapidly growing oncocytomas may warrant intervention, particularly in younger patients.
• Surveillance is a viable alternative for elderly patients or those with comorbidities.