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Sepsis-Induced Cardiomyopathy: a Comprehensive Review
Michael L'Heureux1, Michael Sternberg2, Lisa Brath3
1Division of Pulmonary Disease & Critical Care Medicine, Virginia Commonwealth University, P.O. Box 980050, Richmond, VA, 23298-0050, USA. michael.lheureux@vcuhealth.org.
Current Cardiology Reports
|May 8, 2020
Summary
Sepsis-induced cardiomyopathy (SICM) is often underdiagnosed, impacting patient mortality. Early diagnosis using echocardiography and individualized supportive care are crucial for improving outcomes in these critical patients.
Area of Science:
- Cardiology
- Critical Care Medicine
- Pathophysiology
Background:
- Sepsis-induced cardiomyopathy (SICM) is a significant complication of sepsis, contributing to mortality.
- Understanding the epidemiology and pathophysiology of SICM is essential for effective patient management.
Purpose of the Study:
- To review the current epidemiology and pathophysiology of SICM.
- To provide an extensive review of diagnostic and management strategies for SICM.
Main Methods:
- Review of existing literature on sepsis-induced cardiomyopathy.
- Analysis of diagnostic tools, focusing on echocardiography.
- Evaluation of current treatment guidelines and supportive measures.
Main Results:
- SICM is likely underdiagnosed, carrying significant mortality implications.
- Speckle tracking echocardiography is recommended for diagnosing SICM by identifying decreased contractility.
- Limited large clinical trials exist for SICM treatment; current management relies on supportive care.
Conclusions:
- Individualized work-up and management are critical for improving outcomes in patients with SICM.
- Early recognition and intervention for SICM can mitigate its prognostic impact.
- Further research is needed to establish evidence-based treatment protocols for SICM.
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