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High-throughput Identification of Bacteria Repellent Polymers for Medical Devices

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Published on: November 5, 2016

Bactericidal surfaces prepared by femtosecond laser patterning and layer-by-layer polyelectrolyte coating.

Chao Chen¹, Alessandro Enrico², Torbjörn Pettersson³

¹Department of Fiber and Polymer Technology, KTH Royal Institute of Technology, Teknikringen 56-58, 100 44 Stockholm, Sweden.

Journal of Colloid and Interface Science

|May 8, 2020

Summary

Developing novel antimicrobial surfaces combines laser patterning and polyelectrolyte modification. This creates long-lasting, non-leaching bactericidal surfaces effective against common bacteria like Staphylococcus aureus and Escherichia coli.

Keywords:

Antimicrobial Cationic polyelectrolytes Escherichia coli Staphylococcus aureus Ultrashort pulse laser

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Selective Area Modification of Silicon Surface Wettability by Pulsed UV Laser Irradiation in Liquid Environment

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Published on: November 9, 2015

Area of Science:

Materials Science
Biotechnology
Surface Chemistry

Background:

Antimicrobial surfaces are crucial for preventing infections and biofouling in medical and industrial settings.
Conventional antimicrobial coatings (antibiotics, metals) face limitations like short lifespan and leaching concerns.
There is a significant need for durable, non-leaching bactericidal surface technologies.

Purpose of the Study:

To develop a long-lasting, non-leaching bactericidal surface.
To investigate the combined effect of micro/nanoscale surface patterning and polyelectrolyte modification.
To create an environmentally friendly method for producing advanced antimicrobial surfaces.

Main Methods:

Utilized ultrashort pulsed laser irradiation for micro and nanoscale patterning of borosilicate glass.
Applied a non-leaching layer-by-layer polyelectrolyte modification to the patterned surfaces.
Evaluated the bactericidal efficacy against Gram-positive Staphylococcus aureus and Gram-negative Escherichia coli.

Main Results:

The synergistic combination of surface structure and charge demonstrated enhanced bactericidal activity.
The developed surfaces effectively inhibited the growth of both Staphylococcus aureus and Escherichia coli.
The fabrication processes (laser patterning, layer-by-layer modification) are environmentally friendly.

Conclusions:

This novel approach yields highly effective, long-lasting antimicrobial surfaces.
The method is versatile, applicable to various materials, and suitable for diverse applications.
This technology offers a promising alternative for hygiene products and medical devices, reducing infection risks.