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[A Case of Goblet Cell Carcinoid].
Hideaki Kawakita1, Yoshiaki Ousaka, Fumiaki Kato
1Dept. of Digestive Surgery, Kohsei Chuo General Hospital.
Gan to Kagaku Ryoho. Cancer & Chemotherapy
|May 9, 2020
Summary
A laparoscopic approach may offer a safe and curative option for selected patients diagnosed with goblet cell carcinoid (GCC) after initial appendicitis treatment. Further surgery demonstrated no residual disease, suggesting potential for successful management of this rare appendiceal tumor.
Area of Science:
- Gastroenterology
- Surgical Oncology
- Pathology
Background:
- Goblet cell carcinoid (GCC) is a rare appendiceal neoplasm often diagnosed postoperatively.
- GCC is considered high-grade, with potential for peritoneal dissemination and lymph node metastasis, leading to poor prognosis in advanced stages.
Observation:
- A 26-year-old female underwent interval appendectomy following conservative treatment for acute appendicitis.
- Postoperative pathology revealed goblet cell carcinoid (GCC).
- The patient subsequently underwent laparoscopic ileocolic resection with D3 lymphadenectomy.
Findings:
- The resected specimen showed no residual disease or lymph node metastasis.
- This suggests that a secondary cytoreductive surgery may be a viable treatment option.
Implications:
- Laparoscopic ileocolic resection with D3 lymphadenectomy can be a safe and curative treatment for selected patients with GCC.
- This approach may improve outcomes for patients with this high-grade appendiceal tumor, challenging the typical poor prognosis associated with advanced disease.
