Related Experiment Video
Updated: Dec 22, 2025
Transplantation of Human Induced Pluripotent Stem Cell-Derived Microglia in Immunocompetent Mice Brain via Non-Invasive Transnasal Route
Published on: May 31, 2022
High-Fidelity Modeling of Human Microglia with Pluripotent Stem Cells
Peng Jiang1, Luka Turkalj2, Ranjie Xu1
1Department of Cell Biology and Neuroscience, Rutgers University, Piscataway, NJ 08854, USA.
Abstract:
Gosselin et al. (2017) reported that a tissue-environment-dependent transcriptional network specifies human microglia identity and that in vitro environments drastically alter the human microglia transcriptome. Recent 3-dimensional culture and human-mouse chimeric brain modeling systems developed using human pluripotent stem cells help us understand the complex properties of human microglia.
More Related Videos
11:19Human Microglia-like Cells: Differentiation from Induced Pluripotent Stem Cells and In Vitro Live-cell Phagocytosis Assay using Human Synaptosomes
Published on: August 18, 2022
06:12Author Spotlight: Induced Microglia-Like Cell Technology to Shed Light on the Role of Microglial Dysfunction in Neuropsychiatric Disorders
Published on: September 6, 2024