[The role of vitamin A in the functioning of Golgi apparatus]

Vitamin A participation in the Golgi complex functioning has been studied using the mucosa intermediate area of the chicken glandular stomach as a model. It is shown that in case of A-avitaminosis the electrophoretic profile of soluble proteins of mucosa and [I-14C]acetate and Na2(35)SO4 incorporation into it do not change, while in a secretion all these parameters are highly changed. Four glycoproteins are isolated from the mucous secretion, they differ in solubility in 6% perchloric acid and in staining by kumassi and alcine blue. These data and those obtained before underlie the conclusion that the effect of vitamin A on the secretion formation is realized on the level of the Golgi complex function.