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Updated: Dec 21, 2025

Obtaining Cancer Stem Cell Spheres from Gynecological and Breast Cancer Tumors
Published on: March 1, 2020
Axin2+ endometrial stem cells: the source of endometrial regeneration and cancer
Shafiq M Syed1, Pradeep S Tanwar1
1School of Biomedical Sciences and Pharmacy, University of Newcastle, Callaghan, Australia.
Abstract:
Menstruation is one of the basic but poorly understood life processes in primates during which females shed inner uterine lining every month only to be completely regenerated back within a week. The definitive evidence for the existence and/or identity of stem cells responsible for this process has remained elusive for more than six decades now. Recently, we reported Axin2, a classical Wnt reporter gene, as a marker for endometrial stem cells that also serve as the cells of origin for endometrial cancer.
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