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BIOMEX: an interactive workflow for (single cell) omics data interpretation and visualization
Federico Taverna1, Jermaine Goveia1, Tobias K Karakach1
1Laboratory of Angiogenesis and Vascular Metabolism, Department of Oncology and Leuven Cancer Institute (LKI), KU Leuven, VIB Center for Cancer Biology, Leuven 3000, Belgium.
BIOMEX is a new software tool that helps scientists analyze complex biological data from multiple omics experiments. This user-friendly platform supports various data types, making multi-omics data interpretation accessible to researchers without bioinformatics expertise.
Area of Science:
- Bioinformatics
- Computational Biology
- Genomics
- Proteomics
- Metabolomics
Background:
- The rapid increase in biological data from omics technologies creates analysis bottlenecks.
- Experimental scientists often lack the bioinformatics expertise to interpret complex datasets.
- Accessible tools are needed to facilitate the analysis of multi-omics experiments.
Purpose of the Study:
- To present BIOMEX, a browser-based software designed for the biological interpretation of multi-omics experiments.
- To provide bench scientists with a tool to analyze diverse omics data without extensive bioinformatics training.
- To facilitate the exploration of both newly generated and publicly available omics datasets.
Main Methods:
- BIOMEX integrates statistical tools and algorithms into a flexible workflow.
- The software supports various data types including metabolomics, transcriptomics, proteomics, mass cytometry, and single-cell data.
- It guides users through omics-tailored analyses like normalization, dimensionality reduction, differential analysis, and pathway mapping.
Main Results:
- BIOMEX offers an interactive interface for easy parameter adjustment and customized plot generation.
- The platform accommodates data from different platforms and organisms.
- It provides publication-ready figures for enhanced data visualization.
Conclusions:
- BIOMEX empowers bench scientists to perform complex multi-omics data analysis.
- The software democratizes access to sophisticated omics data interpretation.
- BIOMEX is an open-source tool available to the scientific community.
