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Cutaneous Leishmaniasis in the Dorsal Skin of Hamsters: a Useful Model for the Screening of Antileishmanial Drugs
Published on: April 21, 2012
[Complex cutaneous Leishmaniasis from the "Old World" : Therapeutic challenges in two complicated disease courses]
M Gebhardt1, K Völker2, A Vanegas Ramirez2
1Klinik für Dermatologie, Venerologie und Allergologie, Bundeswehrkrankenhaus Hamburg, Lesserstr. 180, 22049, Hamburg, Deutschland. mariagebhardt@bundeswehr.org.
Abstract:
Here we describe two complicated cases of complex Old World cutaneous Leishmaniasis due to L. infantum and L. aethiopica. Both of our patients infected with the Leishmania parasite presented with a completely different clinical picture, course of disease, and treatment response. Clinical healing was achieved after multiple courses of treatment with a variety of different antileishmanial drugs. Nephrotoxity was a limiting side effect.
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