Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

An Overview of Psychoactive Drugs01:28

An Overview of Psychoactive Drugs

474
Psychoactive drugs impact brain function, influencing perception, mood, consciousness, cognition, and behavior. These substances are grouped based on their effects and the mechanisms by which they act.
Stimulants such as cocaine, amphetamines, and nicotine enhance brain activity, leading to increased alertness, attention, and energy. These drugs typically raise heart rate, blood pressure, and body temperature. While they can induce feelings of euphoria, their misuse can result in severe health...
474
Drug Control Governance: Regulatory Bodies and Their Impact01:03

Drug Control Governance: Regulatory Bodies and Their Impact

413
Drug control governance involves the oversight and regulation of pharmaceuticals to ensure their safety and efficacy while preventing illegal drug use and trafficking. Regulatory bodies, including the US Food and Drug Administration (FDA) and the European Union's European Medicines Agency (EMA), play a central role in this process. These agencies evaluate the safety and efficacy of drugs before they can be marketed. They fund clinical trials and assess the benefits and risks associated with...
413
CNS Stimulants: Psychedelic Agents01:22

CNS Stimulants: Psychedelic Agents

556
Hallucinogens, also known as psychedelic drugs, are a class of substances known for their ability to alter perception, cognition, and emotions. Despite their profound effects on the mind, these drugs are non-addictive, setting them apart from many other abused substances. The mechanism of action of these drugs lies in their impact on the 5-HT2A receptor in the brain. Upon activation, this receptor couples to Gq-type G proteins, triggering a cascade that releases intracellular calcium. This...
556
Drug Regulation01:25

Drug Regulation

2.6K
Drug regulation encompasses the management of drug usage by evaluating its safety and efficacy through assessments conducted by regulatory authorities. Regrettably, the history of drug regulation is marred by several catastrophic events. One such incident is the Elixir Sulfanilamide tragedy, in which the toxic compound diethyl glycol was included in a sweet-tasting medication, leading to numerous fatalities. This event prompted the enactment of the Food, Drug, and Cosmetic Act in 1938. Under...
2.6K
Drug Classes and Categories01:25

Drug Classes and Categories

2.7K
Drugs can be classified according to their chemical composition or their intended therapeutic application. For instance, anti-infective agents that possess the ability to eliminate pathogens or suppress their growth and reproduction can be grouped based on the organisms they target or their chemical structure. Furthermore, drugs can be divided into prescription, nonprescription, or controlled substances. Prescription medications, such as antibiotics, require oversight from a licensed healthcare...
2.7K
CNS Stimulants: Cocaine, Amphetamines and Cannabinoids01:24

CNS Stimulants: Cocaine, Amphetamines and Cannabinoids

666
CNS stimulants, such as cocaine, amphetamines, and cannabinoids, have varying structures and mechanisms of action that lead to different therapeutic effects and side effects. Cocaine, with its molecular formula C17H21NO4, is a tropane alkaloid and a tertiary amino compound. It has two chemical forms: the hydrochloride salt and the "freebase." The former is in powder form, while the latter involves removing the hydrochloride salt to create a form that can be smoked. Cocaine exerts its...
666

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The Development of the Paraphilic Disorders Short Screen (PDSS) and Its Examination in Diverse Populations: A Large, Multi-Nation Study.

Sexual abuse : a journal of research and treatment·2026
Same author

From social media to body image distress: Problematic internet use, exercise addiction, and enhancement drugs use across countries.

Journal of behavioral addictions·2026
Same author

The assessment and treatment of kratom dependence: findings from a physician survey in Malaysia.

The American journal of drug and alcohol abuse·2026
Same author

Captagon: A comprehensive bibliometric analysis (1962-2024) of its global impact, health and mortality risks.

Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society·2026
Same author

Mapping policies related to problematic usage of the internet in seven European countries: Netherlands, Spain, Hungary, Lithuania, Portugal, Estonia and Switzerland.

Comprehensive psychiatry·2026
Same author

Problematic usage of the internet: A policy map of the use of internet and its possible mental health consequences in adolescents across United Kingdom, France, Germany, Italy, Australia, Canada, the United States, and New Zealand.

Comprehensive psychiatry·2026

Related Experiment Video

Updated: Dec 21, 2025

Color Spot Test As a Presumptive Tool for the Rapid Detection of Synthetic Cathinones
06:06

Color Spot Test As a Presumptive Tool for the Rapid Detection of Synthetic Cathinones

Published on: February 5, 2018

26.0K

Global strategy for New Psychoactive Substances: an update.

Balasingam Vicknasingam1, Suresh Narayanan2, Darshan Singh1

  • 1Centre for Drug Research, Universiti Sains Malaysia.

Current Opinion in Psychiatry
|May 14, 2020
PubMed
Summary
This summary is machine-generated.

The global rise of New Psychoactive Substances (NPS) demands updated data collection and collaborative research. Effective strategies involve dynamic legal frameworks and targeting drug networks, not just seizures.

More Related Videos

Rapid High-throughput Species Identification of Botanical Material Using Direct Analysis in Real Time High Resolution Mass Spectrometry
11:14

Rapid High-throughput Species Identification of Botanical Material Using Direct Analysis in Real Time High Resolution Mass Spectrometry

Published on: October 2, 2016

12.0K
High-throughput and Comprehensive Drug Surveillance Using Multisegment Injection-Capillary Electrophoresis-Mass Spectrometry
10:17

High-throughput and Comprehensive Drug Surveillance Using Multisegment Injection-Capillary Electrophoresis-Mass Spectrometry

Published on: April 23, 2019

10.1K

Related Experiment Videos

Last Updated: Dec 21, 2025

Color Spot Test As a Presumptive Tool for the Rapid Detection of Synthetic Cathinones
06:06

Color Spot Test As a Presumptive Tool for the Rapid Detection of Synthetic Cathinones

Published on: February 5, 2018

26.0K
Rapid High-throughput Species Identification of Botanical Material Using Direct Analysis in Real Time High Resolution Mass Spectrometry
11:14

Rapid High-throughput Species Identification of Botanical Material Using Direct Analysis in Real Time High Resolution Mass Spectrometry

Published on: October 2, 2016

12.0K
High-throughput and Comprehensive Drug Surveillance Using Multisegment Injection-Capillary Electrophoresis-Mass Spectrometry
10:17

High-throughput and Comprehensive Drug Surveillance Using Multisegment Injection-Capillary Electrophoresis-Mass Spectrometry

Published on: April 23, 2019

10.1K

Area of Science:

  • Forensic chemistry
  • Public health
  • Pharmacology

Background:

  • The number of New Psychoactive Substances (NPS) has surged dramatically, from 166 in 2009 to 892 in 2018.
  • A significant portion (36%) of NPS exhibit stimulant effects, indicating evolving drug trends.
  • Emerging patterns include a decline in synthetic cannabinoids alongside increased overdose deaths from fentanyl and related compounds in North America and Europe.

Purpose of the Study:

  • To provide an updated review of recent trends in New Psychoactive Substances (NPS).
  • To analyze current global strategies for managing the NPS challenge.
  • To inform policy and intervention development for emerging drug threats.

Main Methods:

  • Systematic review of global NPS trends and seizure data.
  • Analysis of reported cases and scientific literature on NPS.
  • Evaluation of existing international and national control strategies.

Main Results:

  • The emergence of new stimulant NPS has stabilized since 2015, but mephedrone seizures remain below previous international control levels.
  • While synthetic cannabinoid emergence has declined, overdose deaths from fentanyl and related compounds are rising in North America and Europe.
  • The legal status of kratom remains ambiguous, and non-medical tramadol use is a growing concern in Africa and the Middle East.

Conclusions:

  • Addressing the NPS challenge requires enhanced international data collection and collaborative research.
  • Scientific-based interventions and dynamic legal/regulatory frameworks are crucial.
  • Success should be measured by dismantling drug networks, as seizures alone are insufficient to disrupt drug markets.