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Athlete Biological Passport: Need and Challenges.
Dhruv Mahendru1, J Kumaravel1, Vidya M Mahalmani1
1Department of Pharmacology, PGIMER, Chandigarh, 160012 India.
The Athlete Biological Passport (ABP) monitors athlete biomarkers over time, improving anti-doping effectiveness. This longitudinal approach detects performance-enhancing substances that are otherwise hard to identify.
Area of Science:
- Sports Science
- Anti-Doping Analytics
Background:
- The World Anti-Doping Agency (WADA) established the Athlete Biological Passport (ABP) in 2009.
- The ABP aims to enhance the efficacy and robustness of anti-doping efforts.
- Current ABP modules include haematological and steroidal, with endocrinological pending.
Purpose of the Study:
- To introduce the Athlete Biological Passport (ABP) as an anti-doping strategy.
- To highlight the challenges in detecting novel performance-enhancing substances.
- To explain the principle of longitudinal monitoring of biological markers.
Main Methods:
- Longitudinal monitoring of athlete biological markers.
- Interpretation of variations in biomarkers over an athlete's career.
- Utilizing haematological and steroidal modules for data collection.
Main Results:
- The ABP provides an indirect method for detecting prohibited substances.
- It focuses on deviations from an individual athlete's baseline.
- Detection of naturally similar substances like recombinant human erythropoietin is challenging.
Conclusions:
- The ABP represents a significant advancement in anti-doping.
- Continuous interpretation of passport data allows for athlete monitoring.
- Potential for misinterpretation of passport data necessitates careful consideration.
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