Modified endoscopic full-thickness resection of gastric stromal tumor originating from the muscularis propria layer

Endoscopic full-thickness resection (EFTR) is emerging as an approach to resect gastric gastrointestinal stromal tumors originating from the muscularis propria layer (MP-GISTs) because several established endoscopic closure methods and tools have been developed. However, EFTR is performed difficultly due to three challenges: limited luminal insufflation and visualization, insufficient operating space, and inadequate exposure of cutting line. Therefore, we performed a novel method of clip- and snare-assisted EFTR (also named as m-EFTR or chen-EFTR) to resect a MP-GIST. This m-EFTR (chen-EFTR) provides a novel approach to resect MP-GISTs through providing distinct endoscopic visualization, adequate exposure of cutting line and sufficient operating space.