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Fungal Rhinosinusitis: Prevalence and Spectrum in Singapore

Nada A Alshaikh1, Khalid S Alshiha2, Samuel Yeak3

  • 1Otolaryngology, Dammam Medical Complex, Dammam, SAU.

Cureus
|May 14, 2020
PubMed

Insights

Fungal rhinosinusitis (FRS) is common in Singapore, with fungal balls and eosinophilic FRS being the most frequent types. Invasive FRS was not observed in this study.

Area of Science:

  • Otolaryngology
  • Mycology
  • Immunology

Background:

  • Fungal involvement of paranasal sinuses, termed fungal rhinosinusitis (FRS), is a recognized condition.
  • FRS encompasses diverse pathological, immunological, and clinical entities where fungi are implicated.
  • Historical context of fungal sinus involvement dates back over two centuries.

Purpose of the Study:

  • To ascertain the incidence and spectrum of FRS in Singapore.
  • To compare Singaporean FRS findings with international data via literature review.

Main Methods:

  • Retrospective chart review of patients undergoing endoscopic sinus surgery.
  • Analysis of clinical, radiological, and laboratory data, along with operative reports.
  • Study conducted over a five-year period at a tertiary referral hospital in Singapore.

Main Results:

  • Out of 533 chronic rhinosinusitis surgeries, 44 (8.4%) met FRS criteria.
  • Eosinophilic FRS accounted for 20 cases (45.5%).
  • Fungal balls comprised 24 cases (54.5%); invasive FRS was not identified.

Conclusions:

  • Fungal rhinosinusitis is a prevalent condition in Singapore.
  • Fungal balls and eosinophilic mucin FRS are the predominant forms in this region.
  • Findings contribute to understanding the global epidemiology of FRS.
Keywords:
fungal rhino sinusitisprevalencesingaporespectrum

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