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Updated: Dec 21, 2025

A Protocol for Measuring Cue Reactivity in a Rat Model of Cocaine Use Disorder
Published on: June 18, 2018
Elevated C-reactive Protein and Role of Steroids in Cocaine-associated Levamisole-induced Vasculitis
Swetha Ann Alexander1, Vinay Mathew Thomas1, Jacqueline A Savage2
1Internal Medicine, University of Connecticut, Farmington, USA.
Abstract:
Levamisole is a common contaminant in cocaine and has led to the emergence of an entity known as levamisole-induced vasculitis (LIV). There is no consensus on the management of this condition. We describe a patient who presented with acute on chronic LIV who was treated with pulse dose steroids. We aim to discuss the diagnosis and current management options for LIV. We have compared seven case reports that have measured C-reactive protein (CRP) and compared the CRP levels, site involved, dose, and mode of steroid administration. We postulate that elevated CRP may warrant steroid therapy over conservative management and could lead to a possible decreased hospital stay.
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