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Updated: Dec 21, 2025
09:02
Infection of Primary Nasal Epithelial Cells Grown at an Air-Liquid Interface to Characterize Human Coronavirus-Host Interactions
Published on: September 22, 2023
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Human coronaviruses with emphasis on the COVID-19 outbreak
Saraj Bahadur1, Wenxing Long1, Muhammad Shuaib2
1College of Forestry, Hainan University, Haikou, 570228 China.
Virusdisease
|May 14, 2020
Summary
This review summarizes human coronavirus (HCoV) knowledge, focusing on COVID-19's pathogenesis, outbreaks, and control. It details viral diversity, hosts, and geographical spread in China, aiding pandemic understanding.
Area of Science:
- Virology
- Epidemiology
- Public Health
Background:
- Human coronaviruses (HCoV) are significant respiratory pathogens.
- Recent outbreaks of SARS-HCoV, MERS-CoV, and COVID-19 highlight HCoV pathogenicity.
- Understanding HCoV is crucial for managing respiratory diseases and pandemics.
Purpose of the Study:
- To review current knowledge on human coronavirus (COVID-19) in China.
- To summarize viral diversity, reservoir hosts, and geographical distribution.
- To contribute to understanding HCoV pathogenesis, outbreaks, and control measures.
Main Methods:
- Literature review of scientific publications on human coronaviruses.
- Analysis of epidemiological data related to COVID-19 outbreaks in China.
- Synthesis of information on viral characteristics and host interactions.
Main Results:
- As of February 16, 2020, China reported 68,592 cumulative COVID-19 diagnoses, with 1666 deaths.
- The study provides insights into the pathogenesis and outbreak patterns of HCoV, particularly COVID-19.
- Data on viral diversity, host reservoirs, and geographical spread are compiled.
Conclusions:
- This review consolidates current understanding of human coronavirus (COVID-19) in China.
- Findings support the development of effective precautionary measures and public health strategies.
- Further research into viral diversity and host interactions is warranted.
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