Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Chemotherapy-Induced Nausea and Vomiting: Neurokinin-1 Receptor Antagonists01:28

Chemotherapy-Induced Nausea and Vomiting: Neurokinin-1 Receptor Antagonists

445
Neurokinin 1 (NK1) receptors are distributed across the GI tract, vagal afferents, and key CNS regions including the central vomiting center and chemoreceptor trigger zone (CTZ) Chemotherapy agents stimulate enterochromaffin cells in the gastrointestinal (GI) tract to release large amounts of substance P (SP). SP is a neuropeptide released by specific sensory nerves in response to many different stressors, including those in the GI mucosa affected by chemotherapy.  SP binds and activates...
445
Nephrotic Syndrome II : Assessment and Medical Management01:26

Nephrotic Syndrome II : Assessment and Medical Management

143
IntroductionNephrotic syndrome is a kidney disorder marked by excessive protein loss in the urine, leading to various systemic complications. This condition often results from damage to the glomeruli—the kidney's filtering units—causing proteinuria, low blood protein levels, and fluid retention. Understanding the assessment, diagnosis, and management of nephrotic syndrome is essential for effective treatment and prevention of further kidney damage.AssessmentPatient History: Document...
143
Nephrotic Syndrome III : Nursing Management01:24

Nephrotic Syndrome III : Nursing Management

215
Nursing management for nephrotic syndrome adapts as the disease progresses, with strategies evolving to address advancing symptoms and complications.Early-Stage Management In the early stages, nursing interventions for nephrotic syndrome resemble those used in managing acute glomerulonephritis, focusing on symptom monitoring, fluid balance, and managing mild to moderate edema.Vital Signs: Regularly monitor blood pressure, pulse, respiratory rate, and temperature to promptly identify...
215

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Urticaria and Angioedema: When East Meets West-and the Middle.

Allergy·2026
Same author

The International Guideline for the Definition, Classification, Diagnosis and Management of Urticaria.

Allergy·2026
Same author

Subtypes of Atypical Cold Urticaria and Recommendations for Their Diagnostic Workup.

The journal of allergy and clinical immunology. In practice·2025
Same author

The Prurigo Control Test reflects the severity of itch and skin lesions in patients with chronic prurigo: Data from a real-world study.

Journal of the European Academy of Dermatology and Venereology : JEADV·2025
Same author

[The exploratory meeting: Action research on the perspective of care recipients].

Tijdschrift voor psychiatrie·2025
Same author

Acceptability and perceived benefits of validated pruritus assessment instruments in the dermatological office and clinic: The perspectives of patients and physicians.

Journal of the European Academy of Dermatology and Venereology : JEADV·2024
Same journal

Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete·2022
Same journal

[Viral infections of the skin].

Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete·2022
Same journal

[Viral exanthems in children].

Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete·2022
Same journal

[Erratum to: Digital health applications and data protection].

Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete·2022
Same journal

[Virus-induced exanthems in returning travellers].

Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete·2022
Same journal

[Venous ulcus cruris-Surgical treatment].

Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete·2022
See all related articles

Related Experiment Video

Updated: Dec 21, 2025

Cheek Injection Model for Simultaneous Measurement of Pain and Itch-related Behaviors
04:59

Cheek Injection Model for Simultaneous Measurement of Pain and Itch-related Behaviors

Published on: September 27, 2019

12.9K

[Modern systemic therapy for pruritus].

M Metz1, M P Pereira2

  • 1Dermatologische Allergologie, Klinik für Dermatologie, Venerologie und Allergologie, Charité - Universitätsmedizin Berlin, Berlin, Deutschland.

Der Hautarzt; Zeitschrift Fur Dermatologie, Venerologie, Und Verwandte Gebiete
|May 14, 2020
PubMed
Summary
This summary is machine-generated.

Chronic pruritus (CP) is a common, challenging condition. This review covers current systemic treatments and emerging therapies targeting itch signaling pathways for better CP management.

Keywords:
Chronic pruritusClinical trialGuidelinesInnovative substancesNovel drugs

More Related Videos

The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis
11:39

The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis

Published on: July 11, 2013

39.3K
A Mouse Ear Model for Allergic Contact Dermatitis Evaluation
08:02

A Mouse Ear Model for Allergic Contact Dermatitis Evaluation

Published on: March 24, 2023

4.6K

Related Experiment Videos

Last Updated: Dec 21, 2025

Cheek Injection Model for Simultaneous Measurement of Pain and Itch-related Behaviors
04:59

Cheek Injection Model for Simultaneous Measurement of Pain and Itch-related Behaviors

Published on: September 27, 2019

12.9K
The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis
11:39

The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis

Published on: July 11, 2013

39.3K
A Mouse Ear Model for Allergic Contact Dermatitis Evaluation
08:02

A Mouse Ear Model for Allergic Contact Dermatitis Evaluation

Published on: March 24, 2023

4.6K

Area of Science:

  • Dermatology
  • Pharmacology
  • Neuroscience

Background:

  • Chronic pruritus (CP) is a prevalent and burdensome condition.
  • Effective treatment options for CP are limited, especially for severe or refractory cases.
  • Systemic therapies are crucial for managing complex CP cases.

Purpose of the Study:

  • To review current systemic therapies for chronic pruritus (CP).
  • To discuss novel agents and emerging therapeutic targets for CP.
  • To provide an overview of drug indications and patient-specific considerations.

Main Methods:

  • Literature review of systemic therapies for CP.
  • Analysis of current guidelines and clinical study data.
  • Exploration of novel drug mechanisms and targets.

Main Results:

  • Current CP treatment involves diverse, often off-label, systemic drugs (antihistamines, gabapentinoids, etc.).
  • Novel therapies like monoclonal antibodies and JAK inhibitors show promise.
  • Targeting histamine 4 receptors and other neural pathways offers new therapeutic avenues.

Conclusions:

  • A range of systemic therapies exist for CP, with drug selection based on indication and patient factors.
  • Innovative treatments targeting specific pathways are advancing CP management.
  • Further research into novel agents and targets is essential for improving patient outcomes.