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Related Experiment Videos

Schistosomiasis Consortium for Operational Research and Evaluation (SCORE): Its Foundations, Development, and

Daniel G Colley1,2, Julie A Jacobson3, Sue Binder1

  • 11Schistosomiasis Consortium for Operational Research and Evaluation, Center for Tropical and Emerging Global Diseases, University of Georgia, Athens, Georgia.

The American Journal of Tropical Medicine and Hygiene
|May 14, 2020
PubMed
Summary

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The Schistosomiasis Consortium for Operational Research and Evaluation (SCORE) advanced schistosomiasis control through operational research. SCORE

Area of Science:

  • Tropical Medicine
  • Parasitology
  • Public Health

Background:

  • Established in 2008, the Schistosomiasis Consortium for Operational Research and Evaluation (SCORE) aimed to guide schistosomiasis control and elimination strategies.
  • SCORE emphasized collaboration between researchers and national programs, focusing on practical questions for Neglected Tropical Disease program managers.

Observation:

  • SCORE conducted large, multicountry field studies comparing mass drug administration strategies with praziquantel.
  • Evaluated elimination approaches, point-of-care diagnostics for mapping Schistosoma mansoni, and improved laboratory diagnostics.
  • Investigated schistosomiasis morbidity, snail vector quantification, and schistosome population genetics under drug pressure.

Findings:

  • SCORE generated evidence on praziquantel mass drug administration effectiveness and diagnostic accuracy for schistosomiasis.

Related Experiment Videos

  • Research provided insights into disease morbidity, vector dynamics, and genetic parasite responses to treatment.
  • Implications:

    • SCORE's findings offer a robust evidence base to inform policy decisions for schistosomiasis control and elimination programs.
    • Archived data and specimens will support future research, contributing to long-term disease management.