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Updated: Dec 21, 2025

Evaluation of Coronary Flow Reserve After Myocardial Ischemia Reperfusion in Rats
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[Research Progress in Fractional Flow Reserve].

Jiuqing Feng1, Xiaomei Wu2,3,4

  • 1School of Electronic Information, Soochow University, Suzhou, 215006.

Zhongguo Yi Liao Qi Xie Za Zhi = Chinese Journal of Medical Instrumentation
|May 14, 2020
PubMed
Summary
This summary is machine-generated.

Fractional Flow Reserve (FFR) is a key method for assessing coronary artery stenosis severity in heart disease. This review details FFR

Keywords:
Fractional Flow Reservecoronary atherosclerotic heart diseasefunction SYNTAX scoreinstantaneous without wave ratiothe advantages and disadvantages

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Area of Science:

  • Cardiology
  • Medical Imaging
  • Interventional Cardiology

Background:

  • Coronary atherosclerotic heart disease involves coronary artery stenosis, leading to myocardial ischemia.
  • Current diagnostic methods include ECG, blood tests, coronary CT, and angiography.
  • Fractional Flow Reserve (FFR) is increasingly utilized to quantify stenosis severity.

Purpose of the Study:

  • To review the background and significance of FFR in measuring coronary artery stenosis.
  • To explain the basic principles and implementation methods of FFR measurements.
  • To discuss the clinical research, advantages, and disadvantages of FFR, and future technological prospects.

Main Methods:

  • Literature review of domestic and international studies on FFR.
  • Analysis of FFR's principles, implementation, and clinical applications.
  • Exploration of emerging technologies like iFR and functional SYNTAX score.

Main Results:

  • FFR provides a functional assessment of coronary artery stenosis severity.
  • The review details FFR's clinical utility, benefits, and limitations.
  • Future developments in FFR technology show significant potential.

Conclusions:

  • FFR is a valuable tool for evaluating coronary artery stenosis.
  • Further advancements in FFR and related technologies like iFR are expected.
  • These innovations hold promise for improved management of coronary heart disease.