[Research Progress in Fractional Flow Reserve]

Area of Science:

• Cardiology
• Medical Imaging
• Interventional Cardiology

Background:

• Coronary atherosclerotic heart disease involves coronary artery stenosis, leading to myocardial ischemia.
• Current diagnostic methods include ECG, blood tests, coronary CT, and angiography.
• Fractional Flow Reserve (FFR) is increasingly utilized to quantify stenosis severity.

Purpose of the Study:

• To review the background and significance of FFR in measuring coronary artery stenosis.
• To explain the basic principles and implementation methods of FFR measurements.
• To discuss the clinical research, advantages, and disadvantages of FFR, and future technological prospects.

Main Methods:

• Literature review of domestic and international studies on FFR.
• Analysis of FFR's principles, implementation, and clinical applications.
• Exploration of emerging technologies like iFR and functional SYNTAX score.

Main Results:

• FFR provides a functional assessment of coronary artery stenosis severity.
• The review details FFR's clinical utility, benefits, and limitations.
• Future developments in FFR technology show significant potential.

Conclusions:

• FFR is a valuable tool for evaluating coronary artery stenosis.
• Further advancements in FFR and related technologies like iFR are expected.
• These innovations hold promise for improved management of coronary heart disease.