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Neutro"feels" lethal toxin.

Lalita Mazgaeen1,2, Prajwal Gurung1,2,3,4

  • 1Inflammation Program, Infectious Diseases Division, Department of Internal Medicine, University of Iowa, Iowa City, Iowa, USA.

Journal of Leukocyte Biology
|May 14, 2020
PubMed
Summary

Lethal toxins trigger acute interleukin-1 beta (IL-1β) production, a process requiring NLRP1b, caspase-1, PAD4, cell-free DNA, and neutrophils for inflammatory responses.

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