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Updated: Dec 21, 2025

5/6 Nephrectomy Using Sharp Bipolectomy Via Midline Laparotomy in Rats

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Simultaneous versus staged partial nephrectomies for bilateral synchronous solid renal masses.

Vignesh T Packiam¹, Matvey Tsivian¹, Christine M Lohse²

¹Department of Urology, Mayo Clinic, Rochester, MN.

Urologic Oncology

|May 14, 2020

Summary

This summary is machine-generated.

Simultaneous bilateral partial nephrectomy (PN) offers comparable outcomes to staged PN for synchronous renal masses. This approach may provide a reasonable surgical option, with similar oncologic results and potentially better renal function preservation.

Keywords:

Bilateral renal mass Kidney neoplasms Partial nephrectomy Simultaneous Staged

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Area of Science:

Urology
Nephrology
Surgical Oncology

Background:

Management of synchronous bilateral renal masses remains debated.
Surgical sequencing of bilateral partial nephrectomy (PN) is a key consideration.

Purpose of the Study:

To evaluate the impact of simultaneous versus staged bilateral PN on renal function, perioperative outcomes, and oncologic results.
To determine the optimal surgical sequencing for bilateral renal masses.

Main Methods:

Retrospective review of 107 patients undergoing simultaneous or staged bilateral PN (1980-2015).
Assessment of short-term (3 months) and long-term (12 months) estimated glomerular filtration rate (eGFR) changes.
Comparison of perioperative outcomes (length of stay, urine leak, complications) and oncologic outcomes (recurrence, survival).

Main Results:

Simultaneous PN showed significantly less reduction in eGFR at short-term (-6% vs. -24%) and long-term (-4% vs. -22%) compared to staged PN.
Simultaneous PN was associated with shorter length of stay (6 vs. 8 days), lower urine leak rates (3% vs. 17%), and fewer high-grade complications (8% vs. 23%).
No significant differences in oncologic outcomes were observed between the simultaneous and staged PN groups.

Conclusions:

Simultaneous bilateral PN is a viable surgical sequencing approach for synchronous bilateral renal masses when technically feasible.
This approach offers comparable oncologic outcomes to staged PN with potential advantages in renal function preservation and perioperative recovery.