Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

What is Monogastric Digestion?01:50

What is Monogastric Digestion?

74.7K
The human body contains a monogastric digestive system. In a monogastric digestive system, the stomach only contains one chamber in which it digests food. Several other animal species also have monogastric digestive systems, including pigs, horses, dogs, and birds. This chapter, however, focuses on the human digestive system.
74.7K
Anatomy of the Intestines01:23

Anatomy of the Intestines

86.3K
Although digestion of proteins, carbohydrates, and lipids may begin in the stomach, it is completed in the intestine. The absorption of nutrients, water, and electrolytes from food and drink also occurs in the intestine. The intestines can be divided into two structurally distinct organs—the small and large intestines.
Small Intestines
The small intestine is an ~7 meter-long tube with an inner diameter of just 2.5 cm. Since most nutrients are absorbed here, the inner lining of the...
86.3K
Irritable Bowel Syndrome I: Introduction01:17

Irritable Bowel Syndrome I: Introduction

826
Irritable Bowel Syndrome (IBS) is characterized by functional disturbances in the gastrointestinal system, presenting a cluster of symptoms without evident structural or biochemical abnormalities. It primarily affects the large intestine and may cause abdominal pain, bloating, excessive gas, diarrhea, constipation, or both.
IBS is a chronic condition that can persist over a long period or recur frequently.
The pathogenesis of IBS involves a complex interplay of the following factors:
Altered...
826
Bacterial Flora of the Large Intestine01:29

Bacterial Flora of the Large Intestine

1.4K
The gut microbiome is formed by a vast and diverse community of bacteria that colonizes our large intestine. These bacteria start residing in the gut from birth and continue diversifying throughout life, influenced by factors such as diet, lifestyle, and stress. The gut bacterial community also includes bacteria from food and those that enter the colon through the anus.
The normal gut flora of the colon plays a critical role in generating essential vitamins such as vitamins K, B5, and B7.
1.4K
Chronic Bowel Disorders: Introduction01:17

Chronic Bowel Disorders: Introduction

691
Chronic bowel diseases are a group of long-term conditions affecting the digestive tract, characterized by inflammation and damage to the gut lining. These conditions primarily include irritable bowel syndrome and inflammatory bowel disease.
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
691
Microorganisms in Medicine and Therapeutics01:29

Microorganisms in Medicine and Therapeutics

832
Microorganisms play a fundamental role in vaccine development, gene therapy, and therapeutic production. Their biological properties are harnessed to advance medicine and public health. Beyond immunization, microorganisms contribute to gut health, antibiotic synthesis, and genetic disease treatment.Live Attenuated and Inactivated VaccinesLive attenuated vaccines, such as the measles, mumps, and rubella (MMR) vaccine, utilize weakened forms of pathogens to closely resemble natural infections.
832

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Tracking the Trail of Monkeypox: From Origins to Outbreak Control.

Cell biochemistry and function·2026
Same author

Bacillus tropicus KH90 induces systemic drought tolerance in rice: an integrated PGPR-mediated mechanistic framework.

World journal of microbiology & biotechnology·2026
Same author

Metagenomic analysis of bacterial diversity, antibiotic resistance, and functional profiles in the ice core samples from two glaciers of Sikkim Himalaya.

Scientific reports·2026
Same author

Rhamnolipid-like glycolipid biosurfactant mediated degradation of phenanthrene and fluoranthene by Pseudomonas aeruginosa and its impact on soil enzyme activities.

Biodegradation·2026
Same author

First positronium lifetime imaging using <sup>52</sup>Mn and <sup>55</sup>Co with a plastic-scintillator-based PET scanner.

Scientific reports·2026
Same author

Monte Carlo-based scatter correction for the plastic-based modular PET scanner J-PET.

Physics in medicine and biology·2026

Related Experiment Video

Updated: Dec 21, 2025

Microbiota Analysis Using Two-step PCR and Next-generation 16S rRNA Gene Sequencing
11:22

Microbiota Analysis Using Two-step PCR and Next-generation 16S rRNA Gene Sequencing

Published on: October 15, 2019

30.9K

Linking gut microbiota with the human diseases.

Udaya Kumar Vandana1, Naseema Hayat Barlaskar1, Abu Barkat Md Gulzar1

  • 1Department of Biotechnology, Assam University, Silchar, Assam, India.

Bioinformation
|May 15, 2020
PubMed
Summary

The human gut microbiome influences health. Imbalances, or dysbiosis, are linked to diseases like arthritis, cancer, and diabetes. This review explores correcting dysbiosis for better health outcomes.

Keywords:
BacteriaGut microbiomecancerdysbiosisimmunoglobulinshort chain fatty acids

More Related Videos

Applying Advanced In Vitro Culturing Technology to Study the Human Gut Microbiota
06:23

Applying Advanced In Vitro Culturing Technology to Study the Human Gut Microbiota

Published on: February 15, 2019

14.7K
A Gut-on-a-Chip Model to Study the Gut Microbiome-Nervous System Axis
09:18

A Gut-on-a-Chip Model to Study the Gut Microbiome-Nervous System Axis

Published on: July 28, 2023

3.3K

Related Experiment Videos

Last Updated: Dec 21, 2025

Microbiota Analysis Using Two-step PCR and Next-generation 16S rRNA Gene Sequencing
11:22

Microbiota Analysis Using Two-step PCR and Next-generation 16S rRNA Gene Sequencing

Published on: October 15, 2019

30.9K
Applying Advanced In Vitro Culturing Technology to Study the Human Gut Microbiota
06:23

Applying Advanced In Vitro Culturing Technology to Study the Human Gut Microbiota

Published on: February 15, 2019

14.7K
A Gut-on-a-Chip Model to Study the Gut Microbiome-Nervous System Axis
09:18

A Gut-on-a-Chip Model to Study the Gut Microbiome-Nervous System Axis

Published on: July 28, 2023

3.3K

Area of Science:

  • Microbiology
  • Human Health
  • Disease Pathogenesis

Background:

  • The human gut harbors a complex microbial community.
  • Gut microbiota composition is influenced by factors such as hormones, metabolites, and diet.
  • Microbial imbalance (dysbiosis) is implicated in numerous diseases.

Purpose of the Study:

  • To review existing data on the human gut microbiota.
  • To explore the link between gut microbiota and various human diseases.
  • To identify strategies for correcting gut dysbiosis to improve health.

Main Methods:

  • Literature review of scientific data.
  • Analysis of factors influencing gut microbiota.
  • Examination of disease associations with gut dysbiosis.

Main Results:

  • Gut microbiota plays a crucial role in maintaining human health.
  • Dysbiosis is associated with rheumatoid arthritis, cancer, diabetes mellitus, obesity, and cardiovascular disease.
  • Correction of dysbiosis shows potential for disease management.

Conclusions:

  • The gut microbiota is integral to human health.
  • Understanding and modulating the gut microbiota is key to preventing and treating diseases.
  • Further research into correcting dysbiosis is warranted for therapeutic applications.