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Organ function support in patients with coronavirus disease 2019: Tongji experience
Yong Li1, Fan He2, Ning Zhou3,4
1Department of Respiratory and Critical Care Medicine, Department of Internal Medicine, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, China.
Insights
This study details organ support strategies for severe COVID-19 patients. Effective multi-organ support is crucial for improving outcomes and reducing mortality in critical coronavirus disease 2019 cases.
Area of Science:
- Critical care medicine
- Infectious diseases
- Pulmonology
Background:
- Coronavirus disease 2019 (COVID-19) poses a significant global health threat, causing severe multi-organ dysfunction and high mortality rates.
- The lack of specific antiviral treatments necessitates supportive care for severe and critical COVID-19 cases.
- Limited clinical experience exists for managing the complex multi-organ complications of COVID-19.
Purpose of the Study:
- To summarize clinical experiences in multi-organ function support for severe and critical COVID-19 patients.
- To provide a clinical reference for improving cure rates and reducing mortality in COVID-19.
- To propose a new strategy for the optimal treatment of COVID-19 worldwide.
Main Methods:
- Systematic review of functional support therapies for multiple organ systems.
- Focus on respiratory, circulatory, renal, hepatic, and hematological systems.
- Experience-based summary from a specific hospital cohort (Optical Valley Branch of Tongji Hospital, Wuhan, China).
Main Results:
- Detailed procedures for organ function support therapies were outlined.
- The study highlights the critical role of multi-system support in managing severe COVID-19.
- Experience gained provides insights into effective treatment protocols.
Conclusions:
- Multi-organ function support is essential for patients with severe and critical COVID-19.
- The summarized experience offers a valuable clinical reference for global COVID-19 treatment.
- This work contributes to developing optimized treatment strategies for COVID-19.
Abstract:
Coronavirus disease 2019 (COVID-19) is a highly contagious disease and a serious threat to human health. COVID-19 can cause multiple organ dysfunction, such as respiratory and circulatory failure, liver and kidney injury, disseminated intravascular coagulation, and thromboembolism, and even death. The World Health Organization reports that the mortality rate of severe-type COVID-19 is over 50%. Currently, the number of severe cases worldwide has increased rapidly, but the experience in the treatment of infected patients is still limited. Given the lack of specific antiviral drugs, multi-organ function support treatment is important for patients with COVID-19. To improve the cure rate and reduce the mortality of patients with severe- and critical-type COVID-19, this paper summarizes the experience of organ function support in patients with severe- and critical-type COVID-19 in Optical Valley Branch of Tongji Hospital, Wuhan, China. This paper systematically summarizes the procedures of functional support therapies for multiple organs and systems, including respiratory, circulatory, renal, hepatic, and hematological systems, among patients with severe- and critical-type COVID-19. This paper provides a clinical reference and a new strategy for the optimal treatment of COVID-19 worldwide.
