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Gaussian position-weighted center of gravity algorithm for multiplexed readout.

Harutyun Poladyan1, Oleksandr Bubon2,3, Aram Teymurazyan4

  • 1Biotechnology PhD Program, Lakehead University, Thunder Bay, ON P7B 5E1, Canada.

Physics in Medicine and Biology
|May 15, 2020
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Summary
This summary is machine-generated.

A new modified Gaussian position-weighted center of gravity (PW-CoG) technique improves gamma-ray interaction position calculation in positron emission tomography (PET) systems. This method effectively addresses the edge effect in multiplexed detectors, enhancing spatial resolution and image contrast.

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Area of Science:

  • Medical Imaging
  • Nuclear Physics
  • Instrumentation

Background:

  • Readout signal multiplexing reduces electronics cost in positron emission tomography (PET) systems.
  • Center of gravity (CoG) is a common but limited technique for scintillation coordinate calculation.
  • CoG's non-linear response at detector periphery causes an 'edge effect' in multiplexed detectors.

Purpose of the Study:

  • To propose and evaluate a modified Gaussian position-weighted center of gravity (PW-CoG) technique.
  • To overcome limitations of standard CoG in PET detectors with multiplexed readout.
  • To improve gamma-ray interaction position calculation, spatial resolution, and image contrast.

Main Methods:

  • Application of a modified Gaussian PW-CoG technique to PET detectors.
  • Utilized 24x24 LYSO crystals read out by an 8x8 SiPM array with 64:16 row/column multiplexing.
  • Comparison with truncated center of gravity (CoG) coordinate reconstruction methods.

Main Results:

  • Both modified Gaussian PW-CoG and truncated CoG resolved peaks for peripheral crystal events.
  • The PW-CoG algorithm demonstrated superior peak-to-valley ratios.
  • PW-CoG yielded better crystal resolvability metrics compared to truncated CoG.

Conclusions:

  • The modified Gaussian PW-CoG technique effectively resolves the edge effect in multiplexed PET detectors.
  • PW-CoG offers improved performance metrics over truncated CoG for peripheral event reconstruction.
  • This method enhances spatial resolution and image contrast in PET imaging.