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Updated: Dec 21, 2025
An Improved Mechanical Testing Method to Assess Bone-implant Anchorage
Published on: February 10, 2014
Bone ongrowth and mechanical fixation of implants in cortical and cancellous bone
William Robert Walsh1, Matthew Henry Pelletier2, Nicky Bertollo2
1Surgical and Orthopaedic Research Laboratories (SORL), Prince of Wales Clinical School, UNSW Sydney, Kensington, Australia. W.Walsh@unsw.edu.au.
Background:
What is the right surface for an implant to achieve biological fixation? Surface technologies can play important roles in encouraging interactions between the implant surface and the host bone to achieve osseointegration. Preclinical animal models provide important insight into in vivo performance related to bone ongrowth and implant fixation.
Methods:
A large animal model was used to compare the in vivo response of HA and plasma-sprayed titanium coatings in a well-reported adult ovine model to evaluate bone ongrowth in terms of mechanical properties in cortical sites, and histology and histomorphometry in cortical and cancellous sites at 4 and 12 weeks.
Results:
Titanium plasma-sprayed surfaces outperformed the HA-coated samples in push-out testing in cortical sites while both surfaces supported new bone ongrowth and remodeling in cortical and cancellous sites.
Conclusions:
While both HA and Ti plasma provided an osteoconductive surface for bone ongrowth, the Ti plasma provided a more robust bone-implant interface that ideally would be required for load transfer and implant stability in the longer term.
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