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Practical aspects of targeting IL-6 in COVID-19 disease
Cassandra Calabrese1, Prabalini Rajendram2, Gretchen L Sacha2
1Cleveland Clinic CALABRC@ccf.org.
Cleveland Clinic Journal of Medicine
|May 16, 2020
Abstract:
Interleukin 6 (IL-6) took center stage as a therapeutic target, given its role in the cytokine storm phase of COVID-19. While IL-6 inhibitors have been widely used to treat a variety of immune-mediated disease states, they have not been used often in the intensive care setting, and new data question their efficacy. This brief review provides practical information on their administration and safety.

