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Updated: Dec 21, 2025

3D Multicolor DNA FISH Tool to Study Nuclear Architecture in Human Primary Cells
Published on: January 25, 2020
Three-dimensional DNA nanostructures for dual-color microRNA imaging in living cells via hybridization chain reaction
Meng-Mei Lv1, Zhan Wu2, Ru-Qin Yu1
1State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, Hunan University, Changsha 410082, P. R. China. jianhuijiang@hnu.edu.cn.
Abstract:
A well-defined 3D DNA nanostructure with precise composition was developed by stoichimetric combination of a DNA tetrahedron and Y-shaped DNA, which allowed multiplexed, signal-amplified fluorescence imaging of miRNAs in living cells via hybridization chain reaction.
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