Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Microbial Biosensors

Microbial Biosensors

Microbial biosensors are analytical devices that utilize living microbes to detect specific substances through measurable signals. These devices consist of two main components: biosensing organisms and signal-transducing elements. Biosensing organisms, such as Escherichia coli or Saccharomyces cerevisiae, are typically housed in multiwell plates connected to transducers, enabling rapid, real-time detection of target analytes.Signal Generation MechanismWhen a target analyte—such as...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Autodisplay of streptococcal protein G for construction of an orientation-controlled immunoaffinity layer.

The Analyst·2023

Same author

Covalently Immobilized Regenerable Immunoaffinity Layer with Orientation-Controlled Antibodies Based on Z-Domain Autodisplay.

International journal of molecular sciences·2022

Same author

Recent Progress in Electrochemical Immunosensors.

Biosensors·2021

Same author

Efficient Portable Urea Biosensor Based on Urease Immobilized Membrane for Monitoring of Physiological Fluids.

Biomedicines·2020

Same author

A Regenerative Immunoaffinity Layer Based on the Outer Membrane of Z-Domains Autodisplaying <i>E. coli</i> for Immunoassays and Immunosensors.

Sensors (Basel, Switzerland)·2018

Same author

Fabrication of a Urea Biosensor for Real-Time Dynamic Fluid Measurement.

Sensors (Basel, Switzerland)·2018

Same journal

RETRACTED: Zhang et al. A Novel Framework for Reconstruction and Imaging of Target Scattering Centers via Wide-Angle Incidence in Radar Networks. <i>Sensors</i> 2025, <i>25</i>, 6802.

Sensors (Basel, Switzerland)·2026

Same journal

Enhancing Unsupervised Multi-Source Domain Adaptation for Person Re-Identification via Mixture of Experts and Graph-Based Relation.

Sensors (Basel, Switzerland)·2026

Same journal

Development of an Instrumented Glove for Palmar Pressure Assessment in Kayakers.

Sensors (Basel, Switzerland)·2026

Same journal

Development and Experimental Validation of an Autonomous IoT-Based Monitoring System for Real-Time Water Quality Assessment in the Amazon River.

Sensors (Basel, Switzerland)·2026

Same journal

Semi-Supervised Adversarial Learning Framework for Controller Area Network Bus Intrusion Detection.

Sensors (Basel, Switzerland)·2026

Same journal

Smart Optimization Method for Safety Signs in Innovative Manufacturing Environments Integrating Industrial Field IoT Sensors and Knowledge Graphs.

Sensors (Basel, Switzerland)·2026

See all related articles

Search research articles

Related Experiment Video

Updated: Jun 14, 2026

Using Extraordinary Optical Transmission to Quantify Cardiac Biomarkers in Human Serum

Using Extraordinary Optical Transmission to Quantify Cardiac Biomarkers in Human Serum

Published on: December 13, 2017

Surface Display Technology for Biosensor Applications: A Review.

¹Major in Materials Science and Engineering, Hallym University, Chuncheon, Gangwon-do 24252, Korea.

Sensors (Basel, Switzerland)

|May 17, 2020

Summary

This summary is machine-generated.

Surface display technology enables protein expression on cell membranes for diverse applications. This review highlights its advantages and applications in developing advanced biosensors.

Keywords:

bacterial surface display biosensors molecular display molecular recognition layer phage display surface display yeast cell surface display

More Related Videos

Dry Film Photoresist-based Electrochemical Microfluidic Biosensor Platform: Device Fabrication, On-chip Assay Preparation, and System Operation

Dry Film Photoresist-based Electrochemical Microfluidic Biosensor Platform: Device Fabrication, On-chip Assay Preparation, and System Operation

Published on: September 19, 2017

Exploring Biomolecular Interaction Between the Molecular Chaperone Hsp90 and Its Client Protein Kinase Cdc37 using Field-Effect Biosensing Technology

Exploring Biomolecular Interaction Between the Molecular Chaperone Hsp90 and Its Client Protein Kinase Cdc37 using Field-Effect Biosensing Technology

Published on: March 31, 2022

Related Experiment Videos

Last Updated: Jun 14, 2026

Using Extraordinary Optical Transmission to Quantify Cardiac Biomarkers in Human Serum

Using Extraordinary Optical Transmission to Quantify Cardiac Biomarkers in Human Serum

Published on: December 13, 2017

Dry Film Photoresist-based Electrochemical Microfluidic Biosensor Platform: Device Fabrication, On-chip Assay Preparation, and System Operation

Dry Film Photoresist-based Electrochemical Microfluidic Biosensor Platform: Device Fabrication, On-chip Assay Preparation, and System Operation

Published on: September 19, 2017

Exploring Biomolecular Interaction Between the Molecular Chaperone Hsp90 and Its Client Protein Kinase Cdc37 using Field-Effect Biosensing Technology

Exploring Biomolecular Interaction Between the Molecular Chaperone Hsp90 and Its Client Protein Kinase Cdc37 using Field-Effect Biosensing Technology

Published on: March 31, 2022

Area of Science:

Biotechnology and Biomedical Engineering
Molecular Biology and Genetic Engineering

Background:

Surface display is a versatile recombinant technology for expressing proteins on cell membranes.
It is applicable to various biological entities, including viruses, bacteria, and mammalian cells.
Existing applications span drug screening, biocatalysis, library screening, quantitative assays, and biosensor development.

Purpose of the Study:

To review the application of surface display technology specifically in biosensor development.
To present different surface display systems, including phage, bacterial, and yeast cell-based systems.
To summarize the advantages and diverse applications of surface display in biosensors.

Main Methods:

Review of existing literature on surface display technologies.
Detailed presentation of phage display systems.
Description of bacterial (Gram-negative and Gram-positive) and eukaryotic yeast cell surface display systems.

Main Results:

Surface display offers significant advantages for biosensor applications.
Various systems like phage, bacterial, and yeast displays are suitable for biosensor construction.
The technology facilitates diverse biosensing strategies and applications.

Conclusions:

Surface display technology is a powerful tool for creating innovative biosensors.
The choice of display system (phage, bacterial, yeast) depends on specific biosensor requirements.
Continued development of surface display holds great promise for advancing biosensing capabilities.