Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Atherosclerosis III: Management

Atherosclerosis III: Management

Management of atherosclerosis involves an integrated strategy encompassing pharmacological treatment, surgical interventions, lifestyle changes, and nutrition therapy to address the multifactorial nature of the disease.Pharmacological TherapyA cornerstone of atherosclerosis management is the use of pharmacological agents. Statins, such as atorvastatin, are pivotal in inhibiting HMG-CoA reductase, an enzyme that catalyzes an initial step in cholesterol synthesis in the liver. This reduction in...

Coronary Artery Disease IV: Preventive Measures

Coronary Artery Disease IV: Preventive Measures

Effective preventive measures for coronary artery disease (CAD) focus on controlling modifiable risk factors, including cholesterol abnormalities and lifestyle changes.Cholesterol ManagementFirst, the Mediterranean diet and the American Heart Association advocate for maintaining low-density lipoprotein (LDL) cholesterol levels below 100 mg/dL, with a more stringent recommendation of below 70 mg/dL for individuals at high risk. LDL cholesterol, often termed "bad cholesterol," can lead to the...

Hypertension IV: Drug Therapy and Lifestyle Modifications

Hypertension IV: Drug Therapy and Lifestyle Modifications

Multiple classes of antihypertensive medications are employed in treating hypertension. The most commonly recommended first-line treatments include:Thiazide Diuretics, such as chlorthalidone, increase sodium and water excretion from the body, reducing blood volume and blood pressure.Angiotensin-converting enzyme inhibitors, like lisinopril, block the conversion of angiotensin I to II, a potent vasoconstrictor lowering blood pressure.Angiotensin II Receptor Blockers (ARBs) prevent angiotensin II...

Rheumatic Heart Disease III: Medical Management

Rheumatic Heart Disease III: Medical Management

Rheumatic heart disease (RHD) management can be divided into two main strategies: prevention and long-term management.Primary PreventionPrimary prevention focuses on timely diagnosis and management of group A streptococcal pharyngitis to prevent acute rheumatic fever. The most widely used antibiotic for treating this condition is intramuscular benzathine penicillin G.Acute Rheumatic Fever TreatmentThe primary treatment goal for a patient diagnosed with acute rheumatic fever is to suppress the...

Heart Failure V: Medical Management

Heart Failure V: Medical Management

Medical Management of Acute Decompensated Heart Failure (ADHF)The primary goals of therapy for patients hospitalized with acute decompensated heart failure (ADHF) include:Relieving symptomsOptimizing volume statusSupporting oxygenation and ventilationMaintaining cardiac output (CO) and end-organ perfusionIdentifying and addressing the cause of ADHFPreventing complicationsProviding patient education on factors precipitating HF exacerbationPlanning for dischargeOngoing monitoring and assessment...

Cardiomyopathy V: Interprofessional Care

Cardiomyopathy V: Interprofessional Care

Managing cardiomyopathy involves addressing underlying or precipitating causes, treating heart failure with medications, and implementing dietary changes and a balanced exercise and rest regimen.Lifestyle ModificationsCardiomyopathy patients should adopt a low-sodium diet to reduce fluid retention and manage heart failure. A personalized exercise and rest plan helps maintain physical fitness without overstraining the heart. Avoiding alcohol and tobacco is essential to prevent further damage to...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Transcatheter Closure of Patent Foramen Ovale - A Single Center Experience.

The Journal of surgical research·2026

Same author

The History of Coronary Artery Disease.

The International journal of angiology : official publication of the International College of Angiology, Inc·2025

Same author

Acute Kidney Injury after Isolated Coronary Bypass Surgery.

The International journal of angiology : official publication of the International College of Angiology, Inc·2025

Same author

Management of Pulmonary Embolism: A Single-Center Experience.

Southern medical journal·2025

Same author

Long-Term Outcomes of Endovascular Repair of Thoracic Aortic Aneurysms.

The International journal of angiology : official publication of the International College of Angiology, Inc·2024

Same author

Computed Tomography (CT)-Guided Needle Biopsy of Lung Lesions: A Single Center Experience.

Healthcare (Basel, Switzerland)·2024

Search research articles

Related Experiment Video

Updated: Dec 21, 2025

Multidisciplinary Approach to Obesity Management: A Case Report

Multidisciplinary Approach to Obesity Management: A Case Report

Published on: May 30, 2025

Managing Cardiovascular Risk Factors without Medications: What is the Evidence?

Sibu P Saha¹, Melissa A Banks¹, Thomas F Whayne¹

¹Department of Cardiology, Gill Heart and Vascular Institute, University of Kentucky, Lexington, Kentucky, United States.

Cardiovascular & Hematological Agents in Medicinal Chemistry

|May 19, 2020

Summary

This summary is machine-generated.

Therapeutic Lifestyle Changes (TLC), including diet, exercise, and smoking cessation, significantly reduce cardiovascular risk factors. These non-medication approaches are crucial for preventing cardiovascular disease, even when medications are necessary.

Keywords:

Cardiovascular disease cardiovascular risk factor modification coronary artery disease peripheral arterial disease therapeutic lifestyle change vascular disease

More Related Videos

A Novel Digital Platform for a Monitored Home-based Cardiac Rehabilitation Program

A Novel Digital Platform for a Monitored Home-based Cardiac Rehabilitation Program

Published on: April 19, 2019

Hydra, a Computer-Based Platform for Aiding Clinicians in Cardiovascular Analysis and Diagnosis

Hydra, a Computer-Based Platform for Aiding Clinicians in Cardiovascular Analysis and Diagnosis

Published on: September 26, 2018

Related Experiment Videos

Last Updated: Dec 21, 2025

Multidisciplinary Approach to Obesity Management: A Case Report

Multidisciplinary Approach to Obesity Management: A Case Report

Published on: May 30, 2025

A Novel Digital Platform for a Monitored Home-based Cardiac Rehabilitation Program

A Novel Digital Platform for a Monitored Home-based Cardiac Rehabilitation Program

Published on: April 19, 2019

Hydra, a Computer-Based Platform for Aiding Clinicians in Cardiovascular Analysis and Diagnosis

Hydra, a Computer-Based Platform for Aiding Clinicians in Cardiovascular Analysis and Diagnosis

Published on: September 26, 2018

Area of Science:

Cardiovascular Medicine
Preventive Cardiology
Lifestyle Medicine

Background:

Potent medications and interventional procedures often overshadow the importance of lifestyle changes in cardiovascular risk management.
Therapeutic Lifestyle Changes (TLC) are frequently overlooked despite their essential role in cardiovascular risk reduction.

Purpose of the Study:

To emphasize the critical contribution of non-medication approaches, specifically Therapeutic Lifestyle Changes (TLC), to cardiovascular risk modification.
To review and assess available information on TLC and modifiable cardiovascular risk factors.

Main Methods:

A comprehensive review and assessment of existing literature on Therapeutic Lifestyle Changes (TLC).
Analysis of modifiable cardiovascular risk factors including diabetes mellitus, hypertension, hyperlipidemia, tobacco abuse, obesity, stress, and sedentary lifestyle.

Main Results:

Therapeutic Lifestyle Changes (TLC) positively impact all major modifiable cardiovascular risk factors.
Evidence supports the additional benefits of supervised and group-based TLC programs.
TLC, encompassing physical activity, diet, and smoking cessation, is well-established in reducing cardiovascular disease events.

Conclusions:

Therapeutic Lifestyle Changes (TLC) offer significant benefits in cardiovascular disease prevention by addressing metabolic and inflammatory components.
While TLC is crucial, pharmacotherapy is necessary for patients with higher CV risk to achieve optimal cholesterol and blood pressure control.
Motivated patients can achieve significant life extension through dedicated adherence to TLC.