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Updated: Dec 21, 2025

Whole-body PET/MRI of Pediatric Patients: The Details That Matter

Whole-body PET/MRI of Pediatric Patients: The Details That Matter

Published on: December 19, 2017

PET/CT in pediatric oncology.

Gabriele Masselli^1,2, Cristina De Angelis¹, Saadi Sollaku^1,2

¹Department of Radiological Sciences, Oncology and Anatomo-Pathology, "Sapienza" University of Rome Rome, Italy.

American Journal of Nuclear Medicine and Molecular Imaging

|May 19, 2020

Summary

Positron emission tomography/computed tomography (PET/CT) is established in adult cancer care but lacks extensive studies in pediatric oncology. This review explores PET/CT applications for common childhood cancers.

Keywords:

PET/CT oncology pediatric

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Area of Science:

Nuclear Medicine
Pediatric Oncology
Diagnostic Imaging

Background:

PET/CT is a well-established diagnostic tool in adult oncology, supported by extensive research and international guidelines.
Its application in pediatric oncology is less defined due to fewer large-scale studies and concerns about radiation exposure in children.

Purpose of the Study:

To review the current applications of Positron Emission Tomography/Computed Tomography (PET/CT) in the diagnosis and management of common pediatric neoplasms.
To highlight the potential and challenges of utilizing PET/CT in pediatric cancer care.

Main Methods:

Systematic review of existing literature on PET/CT utilization in pediatric oncology.
Analysis of studies focusing on common childhood malignancies and the role of PET/CT in their diagnosis, staging, and treatment response assessment.

Main Results:

While specific data for pediatric oncology is limited compared to adults, PET/CT shows promise in evaluating various childhood cancers.
The review identifies key areas where PET/CT can provide valuable diagnostic information, aiding treatment decisions.

Conclusions:

Further multicentric studies are needed to establish robust guidelines for PET/CT use in pediatric oncology.
PET/CT holds significant potential for improving the diagnostic accuracy and management strategies for pediatric neoplasms, despite current limitations.