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[COVID-19 and cardiovascular diseases: viewpoint for older patients]

Anne-Sophie Boureau1, Laure de Decker2, Gilles Berrut2

  • 1Pôle de gérontologie clinique, CHU de Nantes, Nantes, France, Université de Nantes, CHU Nantes, CNRS, Inserm, Institut du thorax, Nantes, France.

Geriatrie Et Psychologie Neuropsychiatrie Du Vieillissement
|May 19, 2020
PubMed

Insights

Coronavirus disease 2019 (COVID-19) poses risks to patients with cardiovascular disease, increasing their vulnerability and leading to severe outcomes. SARS-CoV-2 infection can also trigger acute cardiovascular complications, highlighting the critical interplay between these conditions.

Area of Science:

  • Cardiology
  • Infectious Diseases
  • Public Health

Background:

  • Coronavirus disease 2019 (COVID-19), caused by SARS-CoV-2, presents significant risks for individuals with pre-existing cardiovascular conditions or risk factors.
  • Older adults and those with cardiovascular issues experience disproportionately worse outcomes when infected with COVID-19.
  • SARS-CoV-2 infection can precipitate acute, life-threatening cardiovascular complications.

Purpose of the Study:

  • To review the multifaceted relationship between COVID-19 and cardiovascular disease.
  • To address concerns regarding cardiovascular comorbidities in COVID-19 patients, including the impact of RAAS inhibitors.
  • To highlight acute cardiovascular complications associated with SARS-CoV-2 infection.

Main Methods:

  • Literature review of current data on COVID-19 and cardiovascular disease.
  • Analysis of patient risk factors and outcomes.
  • Examination of acute cardiovascular events in COVID-19 patients.

Main Results:

  • Patients with cardiovascular risk factors or conditions are at higher risk for severe COVID-19 and adverse outcomes.
  • COVID-19 infection can lead to serious cardiovascular complications.
  • Uncertainty exists regarding the effect of renin-angiotensin-aldosterone system (RAAS) inhibitors on angiotensin-converting enzyme 2 (ACE2) in the context of COVID-19.

Conclusions:

  • Cardiovascular health is a critical consideration in managing COVID-19 patients.
  • Further research is needed to clarify the interaction between RAAS inhibitors and ACE2 in COVID-19.
  • Understanding the cardiovascular impact of COVID-19 is essential for patient care and public health strategies.

Keywords:
COVID-19cardiovascular diseasesmyocardial injuryolder patients

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