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Recent progress in the management of chronic cough
Woo-Jung Song1, Jin An1, Lorcan McGarvey2
1Department of Allergy and Clinical Immunology, Airway Sensation and Cough Research Laboratory, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
The Korean Journal of Internal Medicine
|May 20, 2020
Summary
Chronic cough, often linked to cough hypersensitivity syndrome, significantly impacts quality of life. New research advances understanding and management strategies for this common condition.
Area of Science:
- Respiratory Medicine
- Neuroscience
- Clinical Immunology
Background:
- Chronic cough affects quality of life, with effective treatments still needed.
- Recent advances in understanding cough neurobiology and clinical manifestations are reshaping approaches.
- The concept of 'cough hypersensitivity syndrome' offers a new framework for diverse chronic cough phenotypes.
Purpose of the Study:
- To review recent progress in understanding and managing chronic cough.
- To highlight the clinical relevance of the 'cough hypersensitivity syndrome' concept.
- To identify knowledge gaps and future research directions in chronic cough.
Main Methods:
- Review of mechanistic and clinical studies on chronic cough.
- Analysis of the neurobiological underpinnings of cough.
- Evaluation of the 'cough hypersensitivity syndrome' concept and its phenotypes.
Main Results:
- Accumulating evidence supports the clinical relevance of 'cough hypersensitivity syndrome'.
- A shift in approach to chronic cough is driven by improved neurobiological understanding.
- The allergy and respiratory community increasingly endorses the new diagnostic term.
Conclusions:
- 'Cough hypersensitivity syndrome' is a clinically relevant concept for chronic cough phenotypes.
- Further efforts are needed to integrate this new understanding into routine clinical practice.
- Identifying knowledge gaps is crucial for advancing future research and treatment.
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