Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Tonsillitis II: Management

Tonsillitis II: Management

This lesson will focus on the different treatment options for managing tonsillitis, which typically depend on the cause and severity.

Tonsillitis I: Introduction

Tonsillitis I: Introduction

Tonsillitis is inflammation of the tonsils, which are two lymphoid tissue masses at the back of the throat. This condition can cause discomfort and irritation in the throat.
Etiology
Three primary contributing factors have been identified.

Chronic Pharyngitis

Chronic Pharyngitis

Chronic pharyngitis refers to persistent inflammation of the pharyngial mucosa.
Etiology
It often arises from persistent viral or bacterial infections affecting sinuses and tonsils.
Additional contributing factors include inadequate dental hygiene, mouth breathing, recurring tonsillitis, allergic rhinitis, laryngopharyngeal reflux, and exposure to smoke, chemicals, and other environmental pollutants. Allergic reactions to pollen, mold, and pet dander, chronic cough, excessive voice usage,...

Acute Pharyngitis

Acute Pharyngitis

Introduction
Acute pharyngitis is the inflammation of the back of the throat (pharynx), commonly resulting in a sore throat. It is a frequently encountered condition that prompts individuals to seek medical advice.
Classification
Acute pharyngitis can be categorized based on its underlying cause:

Acute Pyelonephritis II: Diagnostic Studies and Management

Acute Pyelonephritis II: Diagnostic Studies and Management

Introduction:For diagnosing acute pyelonephritis, a comprehensive patient history is collected to identify symptoms such as dysuria, frequent or urgent urination, flank pain, or costovertebral angle (CVA) tenderness that may suggest a kidney infection.Physical ExaminationDuring the physical examination, CVA tenderness is assessed. This involves gentle percussion over the costovertebral angle, where tenderness often indicates a kidney infection.Diagnostic TestsUrinalysis: Used to identify white...

Acute Pyelonephritis I: Introduction

Acute Pyelonephritis I: Introduction

Pyelonephritis is a bacterial infection that primarily affects the renal parenchyma and collecting system, including the renal pelvis, tubules, and interstitial tissue of one or both kidneys. It can be classified as either acute—a sudden, severe infection—or chronic, which refers to long-term or recurrent kidney infections.The primary cause of acute pyelonephritis (APN) is bacterial infection, with Escherichia coli accounting for approximately 70-80% of cases. Other bacteria, such...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Life's essential 8 in relation to incident cardiovascular disease and mortality: the prospective study of Isfahan cohort study (2001-2013).

Archives of public health = Archives belges de sante publique·2026

Same author

Inhibitory Effect of Terminalia chebula Retz. on MDR Shigella flexneri Invasion of HeLa Cells.

Infectious disorders drug targets·2026

Same author

The emergence of pan-drug-resistant <i>Pseudomonas aeruginosa</i> in Iran: A genomic and phenotypic analysis of clinical isolates, multifactorial resistance mechanisms, and its societal impact.

New microbes and new infections·2026

Same author

Diagnostics in cardio-oncology: a focus on anthracyclines.

Heart failure reviews·2026

Same author

Shigella flexneri 1c bacteremia in a child: a case report.

Gut pathogens·2026

Same author

Exploring mesenchymal stem cells as a novel therapeutic approach for HACEK endocarditis: a narrative review.

Journal of cardiothoracic surgery·2026

Search research articles

Related Experiment Video

Updated: Dec 21, 2025

Endaural Endoscopic Atticoantrotomy Retrograde Mastoidectomy using a Constant Suction Bone-drilling Technique

Endaural Endoscopic Atticoantrotomy Retrograde Mastoidectomy using a Constant Suction Bone-drilling Technique

Published on: May 23, 2021

Chronic Suppurative Otitis Media: A Case Report.

M M Karimi Yazdi^1,2, Zohreh Ghalavand², Alireza K Yazdi³

¹Infectious Diseases and Tropical Medicine Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Infectious Disorders Drug Targets

|May 20, 2020

Summary

Chronic Suppurative Otitis Media (CSOM) caused by Pseudomonas aeruginosa can be resistant to common treatments like ciprofloxacin. This case highlights antibiotic resistance and suggests tympanomastoidectomy for persistent infections.

Keywords:

CSOM Pseudomonas aeruginosa chronic fluoroquinolones resistance suppurative otitis media tympanomastoidectomy.

More Related Videos

Long Term Chronic Pseudomonas aeruginosa Airway Infection in Mice

Long Term Chronic Pseudomonas aeruginosa Airway Infection in Mice

Published on: March 17, 2014

A Metadata Extraction Approach for Clinical Case Reports to Enable Advanced Understanding of Biomedical Concepts

A Metadata Extraction Approach for Clinical Case Reports to Enable Advanced Understanding of Biomedical Concepts

Published on: September 20, 2018

Related Experiment Videos

Last Updated: Dec 21, 2025

Endaural Endoscopic Atticoantrotomy Retrograde Mastoidectomy using a Constant Suction Bone-drilling Technique

Endaural Endoscopic Atticoantrotomy Retrograde Mastoidectomy using a Constant Suction Bone-drilling Technique

Published on: May 23, 2021

Long Term Chronic Pseudomonas aeruginosa Airway Infection in Mice

Long Term Chronic Pseudomonas aeruginosa Airway Infection in Mice

Published on: March 17, 2014

A Metadata Extraction Approach for Clinical Case Reports to Enable Advanced Understanding of Biomedical Concepts

A Metadata Extraction Approach for Clinical Case Reports to Enable Advanced Understanding of Biomedical Concepts

Published on: September 20, 2018

Area of Science:

Otolaryngology
Infectious Diseases
Medical Microbiology

Background:

Chronic Suppurative Otitis Media (CSOM) is a significant cause of hearing loss.
Pseudomonas aeruginosa is a common pathogen in CSOM, typically responsive to topical ciprofloxacin.
Antibiotic resistance in CSOM isolates is rarely documented.

Observation:

A 10-year chronic CSOM case in a 24-year-old male due to P. aeruginosa.
Standard treatment with topical ciprofloxacin, suctioning, and pH alteration failed, leading to relapse.
The P. aeruginosa isolate exhibited multi-drug resistance, including to ciprofloxacin, but remained susceptible to colistin and ceftazidime.

Findings:

Genetic analysis revealed two mutations in gyrA and eight in nfxB genes in the P. aeruginosa isolate.
The observed mutations may contribute to the high level of antibiotic resistance.
Tympanomastoidectomy was performed as a definitive treatment.

Implications:

This case underscores the emergence of antibiotic resistance in CSOM pathogens.
Standard CSOM treatments may be insufficient for resistant strains.
Tympanomastoidectomy may be a crucial surgical option for refractory CSOM cases.