Ocular biometric repeatability using a new high-resolution swept-source optical coherence tomographer

To assess the repeatability of ocular biometric parameters using a high-resolution imaging device.

74 healthy right eyes were included in this study. Five-repeated measurements were taken with ANTERION high-resolution swept-source optical coherence tomographer (SS-OCT) to measure: corneal thickness (central and at 2, 4 and 6-mm diameters), aqueous depth (AD), lens thickness (LT), anterior chamber volume (ACV), axial length (AL), and pupil (diameter and position). The intrasubject standard deviation (S_w), coefficient of repeatability (CoR) and intraclass correlation coefficient (ICC) were calculated. Bland-Altman method was applied to analyze the difference between the first and the last measurement. The average and the difference between both measurements were calculated for all parameters.

We have not found statistically significant differences between repeated measurements (p > 0.05). The mean difference for corneal thickness was between -0.08 and 0.28 μm. For AD and LT was 0.004 and -0.004 μm, respectively. ACV mean difference was -0.03 mm³ and for AL was 0.001 mm. Pupil diameter and position mean differences ranged between -0.008 and 0.009 mm. Overall, most ocular parameters had a S_w <1 and a CoR <2 in their respective units, and an ICC >0.92.

The ANTERION high-resolution SS-OCT device provides good repeatability for different ocular biometric measurements.