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Potential SARS-CoV-2 Preimmune IgM Epitopes

Velizar Shivarov1,2, Peter K Petrov3, Anastas D Pashov4

  • 1Laboratory of Clinical Immunology and Department of Clinical Hematology, Sofiamed University Hospital, Sofia, Bulgaria.

Frontiers in Immunology
|May 20, 2020
PubMed

While studying the human public IgM igome as represented by a library of 224,087 linear mimotopes, three exact matches to peptides in the proteins of SARS-CoV-2 were found: two in the open reading frame 1ab and one in the spike protein. Joining the efforts to fast track SARS-CoV-2 vaccine development, here we describe briefly these potential epitopes in comparison to mimotopes representing peptides of SARS-CoV, HCoV 229E and OC43.

Keywords:
B cell precursorsIgMSARS-CoV-2epitopemimotope

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